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  1. Vince

    Is it too late to start hcg?

    Like Phil said it's never too late to start HCG.
  2. Vince

    Good Total T with Low Free T.

    AI The effects of these medications on hormone levels are a complex area of study: Viagra (Sildenafil): Clinical studies have found that Viagra can increase both testosterone and estradiol (a type of estrogen) levels in men with erectile dysfunction and low testosterone. This effect is believed...
  3. Vince

    On TRT: How to check the state of cardiovascular system & how to find heart specialist

    Have you ever had a Heart CT calcium score, checking for plaque? It's normally out of pocket and cost about $120
  4. Vince

    Brain health with trt, missed sleep

    My advice. Don't use Anabolic steroids.
  5. Vince

    Metformin and Its Benefits in Improving Gut Microbiota

    https://www.sciencedaily.com/releases/2025/09/250910000256.htm
  6. Vince

    Good Total T with Low Free T.

    If you can tolerate Viagra/ Cialis It will lower your estrogen and increase your testosterone levels . Also good levels of magnesium will improve your free testosterone. Magnesium increases free testosterone primarily by inhibiting sex hormone-binding globulin (SHBG), a protein that binds to...
  7. Vince

    Is Omega 3 an AR killer??

    AI again Possible mechanisms: It is thought that omega-3s may help by reducing inflammation, which is a factor in cancer development and progression. Omega-3s can also slow the growth and division of cancer cells in lab settings.
  8. Vince

    Is Omega 3 an AR killer??

    AI review Clinical studies on DHA and prostate cancer Investigational drug trials: A Phase II trial studied a DHA-paclitaxel compound for treating metastatic, hormone-refractory prostate cancer to determine its effectiveness and impact on overall survival and quality of life. Dietary and...
  9. Vince

    Men Given Testosterone Enforce Fairness More Readily.

    Very interesting study.
  10. Vince

    Thinking about TRT and could use some guidance

    Based on recent scientific and clinical research, there is evidence supporting the claims that finasteride can alter brain chemistry, potentially cause epigenetic changes, and, in some patients, lead to permanent adverse effects consistent with persistent hormone dysregulation. This cluster of...
  11. Vince

    Injection sites

    I would get a good massager, this is what AI has to say. How massagers help with bumps and scars Improves blood circulation: Massage enhances blood and oxygen flow to skin cells, which promotes faster healing and can reduce the severity of breakouts. Reduces inflammation and puffiness: By...
  12. Vince

    HCT and blood donation

    Yes about 3%
  13. Vince

    Wild ride! Went from 120mg > 100mg > 80mg > 90mg. T is higher at 90mg 3x a week than 100mg 2x a week

    At one time. I injected 100 mg of testosterone twice a week with 500 IU of HCG twice a week. I did feel my best on that protocol. My sleep and and anxiety were both good. No issues. I just could not control my HCT so I lowered my dose and now I inject 16 mg daily and 500 IU of HCG every third day.
  14. Vince

    Hcg from medsbase.com is legit?

    https://www.excelmale.com/threads/prescription-free-online-prescription-recommendations.31548/post-291709
  15. Vince

    Vitamin E, an Antioxidant, As a Possible Therapeutic Agent for Treating Pain

    Remember vitamin e is a absoluble vitamin and you can store. Tocotrienols often offer superior benefits to tocopherols in several areas, including antioxidant activity, cholesterol regulation, neuroprotection, and anticancer potential. This is primarily due to their different molecular...
  16. Vince

    Inject hCG IM for better results?

    For larger injections I definitely would stick with IM. I can understand why people who do daily injections prefer Sub-Q. I'm not one of them I really like shallow IM. For my daily injections I do like to combine both. The days that I combine both testosterone and HCG I always do and have done...
  17. Vince

    Inject hCG IM for better results?

    I do believe the absorption rate is different between Sub-Q injecting in the fat and IM Injections in the muscle. Sub-Q require more frequent injections and IM less frequent injections.
  18. Vince

    Inject hCG IM for better results?

    I would have to agree with @Cataceous when it comes to shallow IM and Sub-Q injections of testosterone. I do both 1/3 of my injections are Sub-Q. I combine both because I do daily injections. When I added in Sub-Q injections. I did not notice a difference in my testosterone levels. My HCG...
  19. Vince

    Injection Frequency 2xs vs 3xs

    I know it's only their total. That's all they had tested.
  20. Vince

    Injection Frequency 2xs vs 3xs

    I do have a friend who in his '60s at his natural T levels are still 1000. I have another friend who is only in his 30s and his levels are only in the 400s.
  21. Vince

    Inject hCG IM for better results?

    I inject 500 IU of HCG every third day. I use an easy touch 29g 1/2-in syringe for a shallow IM in my shoulders. I combined both T + HCG in the same syringe.
  22. Vince

    TRT in Canada if borderline Testosterone and Prolactin?

    Yes, the inverse relationship between dopamine and prolactin is a well-established regulatory mechanism in the body. Elevated prolactin levels generally indicate lower dopamine activity because dopamine acts as the primary inhibitor of prolactin secretion. This regulatory loop is vital for...
  23. Vince

    TRT in Canada if borderline Testosterone and Prolactin?

    Yes, prolactin does work "against" dopamine in the sense that dopamine inhibits prolactin secretion, while prolactin increases dopamine release. This creates a negative feedback loop: when prolactin levels are high, they stimulate the hypothalamus to release more dopamine, which then suppresses...
  24. Vince

    7.5mgs daily labs

    Yes, your statement is correct for many routine testosterone tests: the measurement error of lab assays is often around the same size as, or can be greater than, a person's typical daily variation in testosterone levels. This high variability is why standardized procedures and repeat testing are...
  25. Vince

    Reliable HCG Source?

    I'm still using reliable RX. I have it noticed any price increase.
  26. Vince

    7.5mgs daily labs

    @Cataceous I won't reply about your anxiety or libido issues. I do know you have to do a complete different protocol. I've read your posting. Let's try to keep the thread on track.
  27. Vince

    7.5mgs daily labs

    I agree. I don't know why @Cataceous goes off in different directions.
  28. Vince

    7.5mgs daily labs

    I know @Cataceous cannot use testosterone cyp because of anxiety issues. My understanding is originally he did. I know the half-life of testosterone cyp is approximately 8 days. So when you have Labs 3 hours after injecting compared to 24 hours injecting how much do your levels change? Isn't...
  29. Vince

    7.5mgs daily labs

    Still do it right. If you would post your results from 3 hours to 24 hours it show us how much it varies. At least when it comes to your labs. That way we can have a intelligent discussion.
  30. Vince

    7.5mgs daily labs

    You should do Labs 24 hours after injecting not three.
  31. Vince

    PSA spike

    Yes, mine also double, recently it has been going down and is lowered now. I started TRT at the age of 60, I'm 70 now
Buy Lab Tests Online
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Defy Medical TRT clinic

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