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Yes, men with high free T increase their chances of prostate cancer by 18%

Why do you feel that you need to lower your dose? Because of you free T? What symptoms are you having that make you want to lower your dose? Is it giving you ED issues or low libido. A few of the members with high free t lose their libido and get ED.

I originally just use DHEA 25 mg, later I added pregnenolone. I really don't feel like I need either, only reason. I like to keep my dhea levels in a good range. Try just using the DHEA + see how you feel.

I would just add in the DHEA and skip the the pregnenolone.

I am a coffee drinker. I do wonder how true these studies are. Some studies have shown that caffeine in coffee and tea may reduce dementia risk by a small amount, while other studies show no effect or a slightly increased risk. Alzheimer's Society › ... Caffeine and the risk of dementia |...

I do supplement with both. I have never felt anything from either of the two supplements. Plus have never felt anything from estrogen.

I did skip PDE5i for a few weeks to see if I still would get wood. Surprisingly I did. I was able to have sex in the morning and at night no issues. I really do like the pump I get in my workouts and of course strong wood. Remember I'm not a young man haha

I've been on trt a little over 10 years now. I do feel great. Good workouts, good libido and good energy levels. I'll let you look at my latest Labs if you like. You probably know, but with trt everyone's different. https://www.excelmale.com/threads/vinces-labs-from-october-14-2024.31363/

I do use pregnenolone 10 mg and 10 mg of DHEA. Just to keep my DHEA levels in a good range. Do I feel anything from it? No.

What was the reason that you started TRT and how did you feel before you started?

You can also try the love handles. When I do Sub-Q that's where I inject. I use a 29g 1/2 in syringe.

http://www.k-vitamins.com/

https://www.excelmale.com/threads/vitamin-k-is-associated-with-a-reduced-risk-of-cardiovascular-cancer-or-all-cause-mortality.10281/

I supplement with both k1 and k2 (mk4-mk7)

AI Overview Vitamin K1 and vitamin K2 are both important nutrients for the body, but they have different chemical structures, sources, and biological roles: Chemical structure Vitamin K1 has a shorter chain than vitamin K2, which has isoprenoid side chains in addition to a phytyl side chain...

AI Overview Vitamin K2 MK-4 and MK-7 are both forms of vitamin K2 that differ in their bioavailability, half-life, and potential health benefits: Bioavailability MK-7 is more bioavailable than MK-4, and can be detected in the blood at nutritional levels. Half-life MK-4 has a short half-life...

Look into MK4

Yes, preventative doctors stopped telling patients to use niacin. According to the latest studies, niacin does more harm than good. https://www.nih.gov/news-events/nih-research-matters/how-excess-niacin-may-promote-cardiovascular-disease

https://www.excelmale.com/threads/excess-niacin-causes-blood-vessel-inflammation-and-cardiovascular-disease.29937/post-276091

Apparently it does work for him. But as we all know what works for one doesn't mean it will work for the next person.

https://www.excelmale.com/threads/needing-300mg-a-week.30787/post-285158

@Cataceous You mean this doctor? https://tier1hw.com/personnel/keith-nichols/

When someone is not on TRT. Doctors do recommend increasing your testosterone by exercise, better diet + weight loss. Which in turn will will lower your estrogen. But I never heard of someone increasing their dose of T to lower symptoms of e2.

Interested. Who said to increase testosterone to lower the effect of estrogen? I've never heard that one before.

The ketogenic diet, commonly known as “keto,” and intermittent fasting have gained widespread popularity, attracting everyone from casual fitness enthusiasts to endurance athletes. Both approaches aim to leverage ketosis — a metabolic state in which the body burns fat for energy instead of...

Florence Comite did work at NIH for a long time. She has a lot of experience and I do like her work on trt.

Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life! Hardcover October 8, 2013 by Florence Comite - I read this book a couple of years ago and thought it was really good. I read the kindle version. She talks about men feeling their best, when having their...

I've been supplementing with ps128 for a while now and last night I had my first excellent sleep score. As long as I had my Fitbit watch, I've never had an excellent sleep score. Remember I am 70 years old.

https://www.excelmale.com/threads/vitamin-k-is-associated-with-a-reduced-risk-of-cardiovascular-cancer-or-all-cause-mortality.10281/

I also supplement with high dose K2, MK7 and MK4

Very good post. Honestly though I do not know if it does make that big of a difference. Because my labs very even though I keep the same protocol.