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  1. W

    Can GLP-1 Agonists reverse hypogonadism when metabolic syndrome markers are present?

    Definitely meant sensitivity, whoops. Myself I was on the thinner side like 175-185 and 6’1” and I never tracked my calories, so it’s possible I was under eating and over training. I tried Enclomiphene but stopped about 6 weeks in due to vision problems and strange headaches that felt like they...
  2. W

    Can GLP-1 Agonists reverse hypogonadism when metabolic syndrome markers are present?

    In my never ending quest to try and find some way to reverse my low testosterone I stumbled on some interesting studies about these popular peptides. It seems that for men, taking these class of peptides can actually improve total testosterone perhaps by the way of increasing insulin resistance...
  3. W

    Is nasal spray the only possible fast acting testosterone option? If so, why?

    Appreciate the info, hopefully we see more research in this area soon. I think a lot of the hesitation from current physicians is the fertility risk for their patients. Unfortunately Enclomiphene was the first option I used and I ended up with pretty bad eye floaters. I think that’s just the...
  4. W

    Is nasal spray the only possible fast acting testosterone option? If so, why?

    I am currently only Test C and HCG injections, but I was thinking of possibly moving to the empower nasal spray to save money, but also to maintain natural testicular function. However, I’m a bit concerned about putting gel in my nasal cavity 2x daily for any period of time over a month. I saw...
  5. W

    Never found a root cause to my Low T. Any ideas?

    Ok but do you think these people are both of equal health? Person 1: Total T < 300, SHBG < 20 Person 2: Total T 550, SHBG 60 Free T will be roughly the same, but person 1 arguably has worse blood markers. Person 2 should also have an easier time with injection scheduling. Person 2 also has the...
  6. W

    Never found a root cause to my Low T. Any ideas?

    The way I understood it (may or may not be accurate) is that if SHBG is raised you would have less Free T and subsequently less Free Estrogen which is how the body determines to make more/less T. A normal person should see that their Hypothalamus sends a stronger signal to the pituitary which...
  7. W

    Never found a root cause to my Low T. Any ideas?

    I still think it’s worth checking alongside my A1C again to rule out insulin resistance, especially if I can get insurance to do it. Also the labs shared were all pre-TRT where it was already in the teens. Now it’s almost single digits at 12. The end goal is not to be on thyroid medication and...
  8. W

    Never found a root cause to my Low T. Any ideas?

    Following up on this as I think I might have come across a possible cause for all of this why I suspect could be hypothyroidism. Starting with all of the symptoms: I noticed my hands would get cold and stiff, my memory was shot, I had large weight fluctuations, poor libido, my hair was...
  9. W

    Never found a root cause to my Low T. Any ideas?

    I took viagra prior to TRT and it does work. I am now on TRT and my erections are fine without the need for cialis or viagra.
  10. W

    Never found a root cause to my Low T. Any ideas?

    “As for men, intermittent fasting reduced testosterone levels in lean, physically active, young males, but it did not affect SHBG concentrations” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9182756/ This hormone sucks… From another study “We conclude that insulin and PRL inhibit SHBG...
  11. W

    Never found a root cause to my Low T. Any ideas?

    Maybe some confusion here, but the labs I have shared are prior to any TRT use. I just wanted to share them since I never got a good answer prior to starting TRT as to what I did or didn’t do to cause my low T. As systemlord stated, it could very likely be something beyond my control. Simply...
  12. W

    Never found a root cause to my Low T. Any ideas?

    No DHEA supplements ever. My DHEA maxed out the reference range after starting TRT as did my IGF-1. What would the urine test be for? Why DHT & Preg too? Do you mean a TRT responder? I’ve done pretty well on ED injections. 18mg/day is probably my max tolerated amount before I start breaking...
  13. W

    Never found a root cause to my Low T. Any ideas?

    Yes, I have labs on TRT but not really interested in those. My triglycerides dropped 50 points after starting as well as my LDL which went down to like 100. I did clean up my diet by cutting out the saturated fat as much as possible and any excess sugar because I saw my cholesterol numbers were...
  14. W

    Never found a root cause to my Low T. Any ideas?

    Thanks for the reply, but in regards to SHBG I have ruled out all of those. Obesity - Definitely not, been working since I was 18 Metabolic Syndrome - Again, I’m not obese Diabetes - If I was diabetic I think I would have found out by now and my PCP would have intervened. This leads me to...
  15. W

    Never found a root cause to my Low T. Any ideas?

    Hi, I originally started investigating my low T levels by happenstance when I was 23 and went in for a physical for some erection problems and excessive fatigue. Testosterone didn’t even cross my mind and I didn’t even ask for it on the blood test but it came back at ~313ng/dL. My PCP...
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