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You can try 1-3 tablets of 731 to see if you react at all but yeah, I would first wait for real estrogen. Either pills or cream.

Lol, I was also taking tongkat, zinc, D3 when I crashed with aromasin. Funny (not). Tongkat ali is weird - it's actually a potent AI but in a weird way. I haven't read about ER antagonism but it's possible. Can I please ask you to go do some blood tests? I've been researching these AI crashes...

Oh shit, I'm not sure. I'd have to check with him. The way he told me seemed as if it was like this: he tried 0.25mg and then waited for 1 month. And then took a bigger dose. And so on. He said he was scared that it would backfire, that's why he took lower dose first. This reminds me of a...

@Mttumasov You illustrated it very well hahaha. I have the exact same symptoms. I wouldn't eat the soy supplement. Though, I wonder how you would respond to the popular menopause supplement that contains siberian rhubarb (life extension sells it, for example). Don't bother with morphine...

He tried 0.25mg first then 1mg a month later then 2mg a month after that. He wasnt on TRT during this. Somehow that worked. Those classic E2 pills for women. However, I'm in/I was in contact with many more E2 crashers. Some don't respond to E2 at all. Some respond only to certain forms (so...

Hey @Mttumasov Sorry to hear you're suffering bro. I know one more dude that crashed with arimistane. He is currently on TRT and exogenous E2 injections and feels good. In your case, I would first try e2 pills. I know one dude that recovered 2 years after aromasin crash with few pills of e2...

I agree. I wonder if "natural" 5ar inhibitors would bring similar results. I think not. I think it's how finasteride specifically inhibits 5ar, being a sort of progestin. But I will be trying reishi to see if the mild 5ar inhibition will do anything. Btw, are you planning to do any bloodworks...

Hey bro, hope you are well. I remember we talked about some others atypical antipsychotics. How long are you on zyprexa now? You stopped the other things?

Thanks a lot for this! This is very helpful. High DHT and insulin -- it does actually seem that finasteride is perfect drug for your case. I actually came to the same conclusion but my DHT wasn't high so I didn't want to risk taking fin. Your case seems to justify it. I actually think that long...

Hey bro, thanks for sharing your experience. Very useful. Hopefully it all goes well. Can I ask some questions? 1. The out of breath symptom --- can you explain a bit more what you mean by this? 2. You said you tried estrogen valerate. In which form? Injection, oral pills? What was the dose...

Yeah, these are brutal symptoms. I ask if there are other symptoms (like joint symptoms, sexual symptoms, fatigue, infections, hairloss etc) because as of now I've talked to a dozen of AI crashers and I'm trying to find a pattern. As of now it's apparent reversible AI crash cases shouldn't be...

Any other symptoms besides that? Have you tried exogenous E2, on TRT or off it? Or what other things have you tried? Maybe HCG or anything more exotic? And what do your blood tests say?

I know someone that crashed with aromasin and for 2 years had low E2 symptoms. He fixed himself permanently with few tablets of oral E2. Quite crazy. Another dude fixed himself with many doses of high doses of E2 cypionate injections. However AI crash cases vary too much to figure out an...

This is an extremely complex situation you're in. Forums like these don't understand these conditions. I recommend checking out people that have experience with helping ppl with stuff like this, like joshua leisk's bornfree protocol and alex kikel. Have you had any tests done of any kind...

Btw, this is interesting about your cholesterol levels. Mine were too low for a while as well. Sex steroid levels are high but cholesterol very low. Might be related to thyroid function? Absorption difficulties might be present too. I'll try TUDCA.

Do you guys mind sharing your sources for MIF-1?

This is interesting. So after the surgery you lost erections AND libido? Do you perhaps remember what drugs/meds (if any) you were given prior to surgery?

Thanks. Yeah, estradiol does a lot of stuff. Once you understand how much stuff it's involved in and what it does you understand it's not wise to mess with it. I learned that a bit too late. But I will fix this sooner or later. I think PAIS isn't of one type. Just like PFS and PSSD aren't. PAIS...

(Me being one of those people, lol)

I believe this approach cannot work. This is how mainstream medicine works. Patching up symptoms, making you worse in the long run. It's avoiding treatment of underlying issues. Worse, this cannot work even short-term. A "cabergoline trial" is dangerous. If prolactin elevation is not caused by...

In fact, even before human trials it was already proven on rats that SSRIs cause typical sexual symptoms. Though, for ppl with severe PSSD, sexual symptoms are the least of their worries.

You said you havent taken accutane or finasteride. What about: SSRIs, benzos, antipsychotics? Or what about: saw palmetto, lions mane? Before 2012, have you been taking any medications (antibiotics) or supplements (overdosing on zinc?)? Used any psychedelics, or other drugs? Were you poisoned...

Yes, this is no wonder. Estrogen is crucial for libido. Your e2 levels might be okay but that doesnt tell us if there's proper estrogen signalling taking place. Also, there's balance between ERalpha and ERbeta that serum e2 levels tell us nothing about but is important still.

Bro, his issues have literally everything to do with AI use. That doesn't mean that we ought to focus on e2 levels now. Most people and docs have literally 0 knowledge about the involvement of estrogen in thyroid function (overall metabolism rate), endocannabinoid system, andregenic system...

Did you use AIs on TRT?

Okay, that's interesting. Do you use any supplements?

I would say that if viagra or cialis don't help then the issue is not high E2 in itself. Dropping E2 has a downstream effect on various processes but we would have to find out what exactly does it affect that might be relevant for erections. The dopamine agonist you're using might be playing a...

Have you ever tried supplementing with high-ish doses of alpha gpc? Without acetylcholine with which these nootropics interact it's possible to have erection problems.

PSSD is a way to describe a set of symptoms induced specifically by SSRIs. Many conditions have similar symptoms. Even some long covid cases have symptoms like that. You were predisposed by something so that you reacted this way to few pills of tamox. Don't worry too much, it's reversible. TRT...

There can be underlying issues for which contributing factors most doctors don't care to look for. Typical tests that doctors do can reveal some hints if a competent doctor can interpret them correctly. The fact that you felt like shit is an evidence enough that something was off. And low test...

You're young (saw your profile) so low test levels and feeling shitty would be likely due to some nutrient deficiency. Using TRT can be avoided by making some lifestyle changes, better diet, exercise etc., specific mineral/vitamin supplementation (I know, all sounds bullshit but it's true). It's...