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In my own experience, tweaking the T dosing isn't likely to change the hematocrit much, and yours isn't quite to the 54% mark where most of the experts would suggest either lowering the dose, or giving blood or phlebotomy. However, If you are able, the hematocrit issues could be easily resolved...

I don’t think you will have an issue. It does yield more and better erections, however, they don’t seem to last hours on end, that would put you at risk. The erections come and may last 20-30 minutes but generally not 4 hours, which is when things can get dangerous. If the erections come and go...

A. DON'T inject into the bottom, that is where your urethra is, and it won't help with an erection. The aching you feel post injecting is not uncommon, some men have it more, than others. It is probably due to the prostaglandin in the Tri Mix. I use Tri Mix too, and sometimes I ache after...

I have used branded Vyleesi, but the side effects at the auto injector dose was just to much for me to tolerate. I started using half doses, (about 9 units). Not as good a response, but still helpful. Now my doc tells me Empower has quite making Bremalanotide (PT141). Does anyone know a good...

Your HCT and HBG are at the high end of normal but it sounds like you were at the high end of normal prior to starting HRT too. They usually give folks at clot risk anti thrombotics, regardless of the source. Your cardiac issues put you at a higher risk of a clot. Stay hydrated, take the meds...

No the big driver of HCT and HBG would be iron, especially if taken as supplements in high doses over short periods of time, like days or a week. If your supplements have iron, and some have lots of it, stop those immediately. I have a brother who actually got diagnose with hemochromatosis, a...

It's not likely the estrogen that is causing the delayed ejaculation. Delayed ejaculation can be extremely difficult to diagnose. You could have back problems, higher prolactin, blood flow issues in your penis or prostate, or around the nerves in your genitals, and its seems those who use PD5...

Watch your HCT and HBG closely. If they start to climb, you will need to make changes. If you have any other symptoms, follow up with your Doc. Assuming your Docs will do a cardiac workup on you as well, to be sure something else is not going on with your heart you should be fine. When I say...

It's likely some lab mistake, or a combination of that and dehydration. It seems like in my case, dehydration can easily make a %point or more difference easily. I have apnea also, and my HCT tends to climb up to about 54% about every 4-5 months, but staying hydrated, donating about every 4...

In the words of Sexual medicine trained docs like Rachel Rubin, and Ashley Winter, Dr Goldstein, and others, it's complete and utter baloney. Actually, I cannot report exactly what Dr. Rubin said...it's not fit to print. Let's just say she is not happy with systems that promote themselves with...

I use Akina Pharmacy, and they typically send all their ICI products via 2.5 mm vials pre mixed on ice. (they are also typically less expensive at $189 per 10 ml. they will also produce a "trial vial" 2.5ml for $49 to try it out first) You simply put them in the freezer and take one out, thaw...

I have been using ICI therapies for years now. It is highly likely the bi mix isn't potent enough for you. You would be better served switching or at least trying Tri Mix. It's unlikely the needle length is the cause in my opinion. Why? because the blood flow throughout both cavernosum, takes...

I have a significant degree of ED as well. I have had had total T go from as high as 1800 down to 560 and it makes little difference in the ability to perform. Yes, when I had higher T levels, I had more libido, but that doesn't increase or improve performance in any meaningful way. Do as Madman...

Hi Mark, I do take tadalafil 40 mg daily. I started at 5 mg and worked up from there. My doc is one of the few boarded urologists who is specially trained in sexual medicine. She was comfortable increasing the dose, because the side effects were minimal and the benefit kept getting better. This...

Mark7, in case you did not know, sildenafil or Viagra is not absorbed as well with food too. Especially a meal with a little fat in it, like a good juicy steak. That could be part of why it doesn't work as well. Also I don't know how the doses of tadalafil compare to that of sildenafil, but the...

Hi Mark. After consulting my doc, we decided not to get another. I am likely, unfortunately one of the few who produce antibodies to botox. While it worked unbelievably well the first time, the effect degraded after significantly with each successive shot. The third time it only lasted a few...

I currently take terazosin 2 mg bid for BP control and to help with bph symptoms, along with the higher doses of Tadalafil now up to 40 mg per day. I don’t have E issues, and the Tadalafil works better and better as I went up in dose. A huge improvement. The terazosin is helpful, but I think it...

At 66, sleep is critical for me. If I sleep well, and for enough time each night, I wake up with morning wood before my feet hit the floor. They often come and go, right thru a shower. Days I don't sleep or get good sleep, not much if any. And I can feel the difference throughout the day as...

Bremelanotide or Vyleesi or PT 141 as it's called, is a very effective drug for ED and improving libido. The stuff works extremely well. However, it also has some significant side effects, nausea, body aches, headaches, sinus congestion, and flushing are the predominant ones. If you try it, be...

I have not had it tested for a while but I have been steady on the dose of NP Thyroid for some time now. Symptoms have improved greatly and just not changed. Having said that, my TSH was very low normal range in the therapeutic level. I have no adverse effects. No shaking, no fast heartbeat (if...

Know what you mean. After three endocrinoligists telling me that my Synthroid (T4) "level" was in the middle of the therapeutic window, it's not my thyroid, basically go away. When I started on NP Thyroid, I take 120mg, it was like turning on a light bulb. And amazingly, my symptoms dissipated...

Absolutely true. some may be symptomatic at HCT 52% others might be just fine. its what is contemptuously referred to by those in the medicine as "cookbook" medicine. Problem is X everyone gets drugY, and the response is in the therapeutic window so the patient must be good.....not really. My...

Your evidence makes for good reading but in and of itself, isn't conclusive clinical study. Consequently, it adds cost, worry for perhaps very few people, and based on the more recently clinical studies on testosterone replacement, contradictory in that those show no increased risk of...

This makes sense, but perhaps because they have underlying risk factors a clotting risk in the first place not because of hematocrit per se, but platelet dysfunction...why else would they be on blood thinners?

This is fascinating work. thanks for posting. As one who nearly depleted my iron, it was a stupid decision I made because a primary care doc, not my HRT provider, convinced me I was going to have a stroke if my HCT didn't come down. He then sent me to hematologist, who was more knowledgeable...

Topical maybe, but oral finasteride is bad deal. Finasteride has too many side effects, and puts your penis at risk. Long term finasteride use is associated with severe ED problems among others.

alcohol has a very low residue level. She would have to be extremely sensitive to it. Are the pads you use, just an alcohol based pad? It may be other chemicals in the pad. I would make sure they are medical grade alcohol, without anything added to it. Lens cleaners for instance are mostly, but...

In my quest to conquer ED, I have tried and reported here on my experience with Vyleesi branded, PT 141 (EM power), Tri Mix, Quad Mix, Botox, PRP injections (P Shot), Shockwave ( a real clinic quality system given by an experienced physician). One of the benefits of being treated by an...

I have used both PT 141, Branded Vyleesi (same thing but auto injector and 1.5mg dose) and tadalafil, and Tri Mix. I have significant ED post prostate cancer treatment. This is really a case of know thyself. If you get a good response to a great response from any of the above, when combining...

I have pretty sever ED, that had started before I was diagnosed with prostate cancer. I was treated for the cancer with radiation therapy. Over time, it created significantly more ED issues, as its damage to your prostate happens over a period of months to years. Currently I take 15 mg of...

I'd suggest asking your doc to test you for Hashimoto's thyroiditis. If your body is producing antibodies to your thyroid gland, even though you levels are not yet low, it would explain the aches to some degree. Your symptoms do seem to match up to being hypothyroid, but your numbers suggest...