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I have the same experience as OP @eli. Mast, proviron, arimidex, aromasin all gave me nothing but trouble no matter how little I microdose. Two things have worked: Primo and DHT itself

I have not used alcohol swabs in years and experienced 0 issues with infection. Even if the vial/skin was unclean, the benzyl alcohol in the solution acts as an antibacterial. To my understanding the % of benzyl alcohol should range between 1-2% of solution. For antibacterial purposes, it...

Anastrazole makes me feel mentally terrible at any dose (even half of a quarter pill). Always gave me "low E2" feelings of depression. A bit unconventional but you could simply try a few drops of transdermal DHT when you feel E2 peaking from the HCG. Very fuss-free, dose-adjustable, and it...

Great recommendation, thanks. Curious to know if you would consider masteron enanthate for the same purpose?

There is a misunderstanding - I agree that Proviron doesn't cause high E2. But because it does lower E2, I'm forced to dose a higher base level of testosterone (otherwise I will get low E2 symptoms). And because the proviron gets broken down so quickly, the higher base level of T then creates...

I've had decent success with Proviron for libido but my issue is with its short half-life of 12 hours which causes lots of ups and downs. At the higher doses (50mg onwards) I can literally go from low E2 symptoms to feeling horny/euphoric to high E2 symptoms... within the same day! On a side...

I've taken 3 rounds of Accutane in my life and each time I felt my energy levels dwindle a bit more. Now that I'm on HRT I don't feel good on normal doses (100-150mg test) possibly because of long-lasting 5AR downregulation. I feel like complete crap on those doses. I need at least 180-200mg...

We are in the exact same boat brother. I tried raising my low e2 for YEARS and nothing worked. Not HCG, not more test, not even e2 gel (Oestrogel only worked for a few days). I only got temporary relief of brain fog and joint pain when I supplemented with Cat's Claw (Uncaria Tomentosa) but it...

Not at all. I never have to now, which I'm really thankful to the E2 cyp for.

T dose is 180mg/week with injections every 2 days. My last E2 test was 31 (TT was 1200) and I still felt like crap. T:E ratio was nearly 40:1. Yeah there's just something about E2 cypionate. If you trawl through the trans MtF forums, you'll see some anecdotes that cypionate is more potent mg...

28 this year. Body fat around 14% (I can see my abs if I squint hard enough under good lighting lol). Libido and EQ are at least a solid 8/10 on most days, 9/10 if I go a few days without any action. My TRT dose is on the higher side though. We don't have the proper tests for FT and E2 here but...

Update on my estradiol supplementation: Switched from estradiol valerate to cypionate and my dosing requirement has reduced drastically but I am feeling better than ever. For two months, I have been taking 0.3mg every 2 days and feel fantastic on it. I'm using a 5mg/ml solution. I feel...

Here's my n=1 experience: For about 2.5 years I did not include HCG with my TRT and now that I have included it back in at 500iu every other day, my balls are still not as large as how they used to be. Granted, this seems to be more of an aesthetic than a functional issue since many guys are...

Much appreciated on the clarification. If I may further tap on your knowledge - is it at all possible to monitor E2 or FT levels if there are no laboratories in my country that performs the LC-MS (for E2) and Equilibrium Dialysis (for FT)? For example, I've heard the ECLIA test for E2...

Thanks for your comment, I stand corrected that my TT explanation is logically insufficient. I'd like to point out an issue with the study you quoted on the 14 transgender males though. Looking at the actual study, I notice that the IM readings were taken on week 3, but the SC readings were...

Hi madman, I think you misunderstood what I said. Do you notice I used a qualifying statement on the drop in FT? I said - "if the labs are directionally accurate". I'm not ruling out the assay method which is what you're arguing for (I actually agree that is a huge issue!). I'm sure...

MarkM, thanks for your valuable insights. You did a huge service to all of us by posting those results. Here's my personal analysis on your subq experiment: TT falling was to be expected. Subq depots are absorbed more slowly into the bloodstream after all. What's interesting was it fell by over...

I have an interesting update to share. Before, I needed 2mg of estradiol valerate per day (1mg subq, 2x/day) to feel good. I have since found that intramuscular shots of EV work twice as good. Even better - the effects last way longer. So now I only have to do 1mg every 2 days, which is great...

Yeah, I found it odd myself that I needed such a high dose of Estradiol Valerate to feel good. Either my E2 receptors are not functioning properly, or that serum E2 is not translating into tissue E2, or I'm getting low-purity raw powders.

Interesting, that would mean you feel best on a T:E ratio of 10:1. (I assume this is the sensitive E2 test?) I'm also finding the ideal E2 dose. Currently 2mg/day of estradiol valerate (1mg subq, morning and evening) with 250mg/week of TRT helps me feel good. I simply feel like crap on any...

My test dose was around 180mg/week at the time. Have tried 150mg/week and below before, just doesn't make me feel well no matter how dialed in my E2 is.

I was using between 25-50mg aromasin per day, for 3 months. And then I stacked letrozole on top of that. I was just stupid at the time, I know. I convinced myself I was the only person in the world who had high E2 while on letro + aromasin.

Allow me to join in here. I have the same low E2 problem as a few others here, caused by abusing stupid amounts of aromasin several years ago. Here's what hasn't worked: Increasing test dosage. At one point I was doing 400mg/week and still getting low E2 symptoms. HCG. Just helps to a very...