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  1. Vince

    Sleep deprivation impacts us in various ways

    There have been quite a few research studies on lack of sleep, like how it can increase the risk of heart attack and stroke, contribute to brain aging, and even make you feel drunk at work (not as fun as it sounds.) If you don’t get enough REM sleep, your brain has trouble maintaining all sorts...
  2. Vince

    Surgeon General Calls for Cancer Warning Labels on Alcohol

    I didn't know alcohol contributes to cancer.
  3. Vince

    The danger of doing your own research.

    In 1995, McArthur Wheeler and Clifton Earl Johnson robbed two banks in Pittsburgh. They believed they wouldn't be caught because they had researched how to render themselves invisible to bank security cameras. They learned that lemon juice could be used to write an invisible message on paper...
  4. Vince

    Some foods may increase the risk of prostate cancer, while others may help reduce the risk.

    Some foods may increase the risk of prostate cancer, while others may help reduce the risk: Red and processed meat Eating red meat, like beef, pork, lamb, or goat, and processed meat, like bacon, ham, and sausage, may increase the risk of prostate cancer. This may be due to heterocyclic...
  5. Vince

    A Stanford-led team discovered a new ketosis pathway.

    The ketogenic diet, commonly known as “keto,” and intermittent fasting have gained widespread popularity, attracting everyone from casual fitness enthusiasts to endurance athletes. Both approaches aim to leverage ketosis — a metabolic state in which the body burns fat for energy instead of...
  6. Vince

    The Loss of Estradiol by Androgen Deprivation in Prostate Cancer Patients Shows the Importance of Estrogens in Males

    The role of estradiol (E2; an estrogen) in men needs to be more appreciated. In this review, we address the clinical situations that allow the study of the clinical consequences of E2 deficiency in men and discuss the effects of restoration of levels of this reproductive steroid hormone. In men...
  7. Vince

    Today marks my 10th anniversary of TRT!

    Today marks a decade of incredible experiences at Excelmale! I'm incredibly grateful for the Members that helped grow and contribute, and I look forward to many more years here. Thank you everyone for making this journey so rewarding.".
  8. Vince

    Orville Rogers (age 100) stated, “I love the thrill of preparation and training,” he told Runner’s World.

    https://www-cbsnews-com.cdn.ampproject.org/v/s/www.cbsnews.com/amp/texas/news/orville-rogers-dallas-record-breaking-running-man-passes-away/?amp_gsa=1&amp_js_v=a9&usqp=mq331AQIUAKwASCAAgM%3D#amp_tf=From%20%251%24s&aoh=17330612034650&referrer=https%3A%2F%2Fwww.google.com&ampshare=https%3A%2F%2Fwww...
  9. Vince

    What percent is placebo?

    AI Overview The percentage of results that are placebo varies depending on the study type and condition being treated, but can range from 21% to 40%: Placebo-controlled trials The average placebo response in placebo-controlled trials is 34%. Antidepressant clinical trials The mean placebo...
  10. Vince

    Vince's Labs from October 14, 2024

    Same protocol, 16 mg of testosterone cypionate daily, 500 iu of hcg every third day and no AI. Pregnenolone 10 mg and 10 mg of DHEA. My last injection before labs, about 27 1/2 hrs. Labs are from LabCorp. I did "not" get the Equilibrium Ultrafiltration for testing free testosterone. I...
  11. Vince

    Survival of the fittest: VO2max, a key predictor of longevity?

    Cardiorespiratory fitness, as measured by maximal oxygen uptake (VO2max), is related to functional capacity and human performance and has been shown to be a strong and independent predictor of all-cause and disease-specific mortality. The purpose of this review is to emphasize age-related...
  12. Vince

    The strange reason why your body ages most rapidly between 44 and 60.

    Changes may influence health and disease risk In people in their 40s, significant changes were seen in the number of molecules related to alcohol, caffeine and lipid metabolism; cardiovascular disease; and skin and muscle. In those in their 60s, changes were related to carbohydrate and caffeine...
  13. Vince

    Constipation is linked to cognitive decline and dementia.

    Yes, chronic constipation is linked to cognitive decline and dementia: Cognitive decline A study of over 100,000 adults found that those who had a bowel movement every three days or more had cognitive decline equivalent to three years of aging. Dementia Dementia patients with constipation...
  14. Vince

    I was wondering if any members use L plantarum PS128 for mental health?

    Clinical Application Value of Lactobacillus Plantarum PS128 in Patients with Anxiety Disorders PS128 is a novel psycho biotic strain, it has been reported to play an important role in neuropsychiatric disorders. This study investigated the clinical effect of PS128 supplementation on patients...
  15. Vince

    Yes, a man in his 80s can still have good muscle mass

    Yes, a man in his 80s can still have good muscle mass, and in fact, research shows that it's never too late to start building muscle: Muscle loss is normal As people age, it's normal to lose muscle mass, strength, and function, a condition called sarcopenia. This process can start as early as...
  16. Vince

    Canada Wide Pharmacy

    I was wondering if anyone knows Canadian wide pharmacy is it legit and safe to use? I would like to order a med from them and have it shipped to the USA.
  17. Vince

    ODS Invites Public Comment on Draft Strategic Plan

    The Office of Dietary Supplements (ODS) at the National Institutes of Health has initiated a strategic planning process that will culminate in the publication of the ODS Strategic Plan for 2025–2029. To assist with this process, ODS requests input from research communities—academic, government...
  18. Vince

    52 Good Morning Quotes to Bring You Daily Clarity

    https://www.marcandangel.com/2024/07/08/52-good-morning-mantras-that-will-change-your-life/
  19. Vince

    8 Wake-Up Calls Everyone Needs to Receive in Life Before it’s Too Late

    https://www.marcandangel.com/2024/06/11/8-little-wake-up-calls-you-need-to-receive-before-its-too-late/
  20. Vince

    Fish oil supplements linked to greater first-time heart attack risk in study: ‘Not universally good or bad'

    Among healthy people, regular use of fish oil was found to make them more susceptible to developing heart disease and stroke for the first time, the study found. Among those who had existing heart disease, however, fish oil consumption was shown to slow the progression of cardiovascular disease...
  21. Vince

    Unexpected Connection Between Menthol And Alzheimer's Discovered in Mice

    https://www.sciencealert.com/unexpected-connection-between-menthol-and-alzheimers-discovered-in-mice
  22. Vince

    A recent analysis found that people with very high HDL levels (80 mg/dL or higher)

    Past observational studies in large groups of people have shown that those with higher HDL levels (above 40 mg/dL for men and 50 mg/dL for women) tend to have fewer heart attacks. And until recently, the general belief was the higher the HDL level the better. However, a recent analysis found...
  23. Vince

    Does magnesium decrease SHBG?

    Does magnesium decrease SHBG? Magnesium binds SHBG in a nonspecific mode, leading to an uncompetitive inhibition with T in binding SHBG and to a subsequent enhancement of Bio-T availability. The binding is accompanied by a magnesium release (or uptake) with a corresponding heat effect around...
  24. Vince

    Vince's Labs from 4/15/24

    My protocol, 16 mg of testosterone cypionate daily, 500 iu of hcg every third day and no AI. Pregnenolone 10 mg and 10 mg of DHEA. My last injection before labs, about 27 1/2 hrs. Labs are from LabCorp. I lowered my dhea from 25 mg to 10 mg daily, it may have lowered my E2. Used black cumin...
  25. Vince

    Berberine, slow the progression of REM Sleep Behavior Disorder and Parkinson's Disease.

    https://rbd-pd-protocols.blogspot.com/p/berberine.html
  26. Vince

    PSA Levels by Age: What Every Man Needs to Know About Prostate Health

    Generally, here are the normal PSA levels by age group: 0-2.5 ng/mL: Normal for men ages 40-50 2.5-3.5 ng/mL: Normal for men ages 50-60 3.5-4.5 ng/mL: Normal for men ages 60-70 4.5-5.5 ng/mL: Normal for men ages 70-80...
  27. Vince

    Swapping red meat for herring, sardines and anchovies could save 750,000 lives, study suggests

    https://www.theguardian.com/food/2024/apr/09/swapping-red-meat-for-herring-sardines-and-anchovies-could-save-75000-lives-study-suggests
  28. Vince

    written by midlifealpha, Is anyone here getting any reliable hair loss products?

    this was written by @midlifealpha We can probably move this thread but I am perusing Reliable at the moment and they seem to have the Bimatoprost cheap. I'm not sure what other hair products they offer but years ago when ours shot up to $350 at Defy I just gave up. Is anyone here getting any...
  29. Vince

    The Y Chromosome Is Vanishing. A New Sex Gene May Be The Future of Men.

    https://www.sciencealert.com/the-y-chromosome-is-vanishing-a-new-sex-gene-may-be-the-future-of-men
  30. Vince

    Rocky’ Star Carl Weathers’ Cause of Death Revealed

    https://www.yahoo.com/entertainment/rocky-star-carl-weathers-cause-222156888.html
  31. Vince

    Men who are deeply unhappy displayed these behaviors.

    https://geediting.com/men-who-are-deeply-unhappy-in-life-often-display-these-behaviors-without-realizing-it/
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