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Please Help! Confusing Bloodwork and Hypothyroid symptoms

Please help me understand my blood work and symptoms I’ve been struggling for the longest time with fatigue, stubborn weight, and feeling extremely cold + sluggish, constipated and having ED. I’ve been taking my oral temperature on waking and throughout the day. Waking temp ranges from 92-96...
- AhmetAtay
- Thread
- Nov 25, 2022
- bloodwork free t3 free t4 hypothyodism t3 t4 tsh
- Replies: 6
- Forum: Thyroid, DHEA, Pregnenolone, Progesterone, etc
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I need help with Low E2. I’m at my wits end.

I’ve been struggling with low E2 for the longest time. Started off my TRT 36 mg daily test CYP, 200 IU HCG daily, and 0.0625 mg anastrozole twice per week. Dropped the AI due to low E2 symptoms (mostly achy knees, lethargy, difficulty maintaining/getting erection). Bloodwork showed T = 3100...
- AhmetAtay
- Thread
- Nov 4, 2022
- estradiol estradiol crash
- Replies: 3
- Forum: Testosterone Side Effect Management
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Headaches, dizziness and lethargy

Old protocol was 200 mg split into daily administrations with 250 IU HCG EOD Bloodwork revealed elevated RBC (6.20 million/uL), normal hematocrit (43.4) and low Hemoglobin (13.0). I expected my hemoglobin to be low because I have beta thalassemia trait. Pre-TRT my hemoglobin was 10.0 and my RBC...
- AhmetAtay
- Thread
- Oct 15, 2022
- dizziness high rbc lethargy vertigo
- Replies: 8
- Forum: Testosterone Side Effect Management
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Melatonin Preventing Estrogen-Mediated Gene Transcription In Vitro

This study (Melatonin blocks the activation of estrogen receptor for DNA binding - PubMed) seems to show that melatonin hinders the action of estrogen-bound estrogen receptors. "The present study shows that melatonin prevents, within the first cell cycle, the estradiol-induced growth of...
- AhmetAtay
- Thread
- Oct 13, 2022
- aromatase inhibitor estradiol melatonin
- Replies: 11
- Forum: Testosterone Basics & Questions
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Hands Swelling At Night

For the past week or so I've been experiencing some notable swelling in my fingers when I lay down to sleep at night. It gets bad enough to where I wake up at night because my right hand is totally numb and then I have to awkwardly shift sleeping position. My protocol is currently 20 mg test C...
- AhmetAtay
- Thread
- Sep 28, 2022
- carpal tunnel dhea edema on trt hcg pregneneolone swelling water retention
- Replies: 5
- Forum: Testosterone Side Effect Management
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Help! Insomnia, Irritability, and Libido Issues on TRT

Here's my most recent bloodwork with an SHBG of 38 I was on 250 mg test C split into daily injections as well as 150 IU HCG ED. I was also taking 100 mg pregnenolone before bed because my pre-TRT progesterone was 0.1 I have been waking up too early (after 6 hours in bed) and unable to go back...
- AhmetAtay
- Thread
- Sep 9, 2022
- hcg + trt insomnia libido pregnenolone
- Replies: 25
- Forum: Questions for Specific Doctors & Experts

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038