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    My optimal protocol is daily injections of Estrogen and just 24.5mg Test per week

    I first started TRT with far too much for far too long 250mg of T Cyp/week. None of my symptoms (crippling fatigue, very low libido etc. improved) Browsing through the internet, I even tried Aromatase inhibitors incase high E conversion was preventing benefits, but that didn't work. When I...
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    Accidentally took a megadose of Estradiol in place of Testosterone

    I've been very foggy after dealing with a thiamine paradox reaction that won't go away (long story - I have CFS, so used thiamine to treat it). Hence this morning, instead of TRT I pinned Estradiol Valerate without realising. The dose was 20mg - which is roughly equivalent to 40 oral 2mg...
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    OPEN STUDY: What levels of free T, Testosterone, E2, prolactin, cortisol do you feel best at?

    All of us are following our protocols quite blindly, trying to optimise but unsure what values to optimise to. The lab ranges vary between countries and labs. The NHS for example sets it upper T limit at 750 - whereas many people in the US naturally have higher levels than this and are perfectly...
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