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I felt that same feel good/calming sensation that I noticed before from the scrotal cream as well, just less than the cream though. Sleep a bit deeper and my nap in the afternoon also feels more restful. I'm not sure if that's Progesterone itself or some metabolites. I'm only at day two though...

how long in between dose adjustments were you waiting to check levels? or when do you think steady level is achieved with SC Progesterone in oil? I couldn't find any data on this. I just started last night with 1.5mg, I believe I already felt it, it could be placebo thought.

Hi Vince, are you also on injectable Progesterone?

Im wondering if all subQ injection site yield to same absorption/levels of injectable medication. I would guess yes, but especially curios to hear anecdotes Im about to start Progesterone subQ but didn’t have good luck with testosterone SubQ, I was injecting on the upper outer part of the...

I find conflicting data on the daily production of Progesterone in men. The above study shows 5 to 15mg, which seems allot to me, the study below shows 1.5 to 3mg daily https://www.sciencedirect.com/topics/nursing-and-health-professions/progesterone " Hormone Replacement in Men Alicia...

@Gman86 I don't mean to be negative or anything, I just thought about you.

Thanks, if it wasn’t for you and cataceus we wouldn’t have any guidance on dosing. I believe Progesterone really balance testosterone, the more of one, will possibly require more of the other

It is! I just called my doc and asked for a reduction in concentration to 50mg/ml, I believe empower carries a pharma grade for this, probably what you showed me in the pic The maximum I got from the Pregnenolone caps or scrotal Progesterone was .5 or .7, I would look at least to get to...

according to this paper, men produce anywhere from 0.416 to 0.75 mg/day of Progesterone "The production rate of endogenous progesterone and hence the natural progesterone levels inplasma show a large variation, depending on the species, sex, age and physiological status. Inhumans, the...

thanks. My doc just approved a 100mg/ml, I think 50mg/ml may help better with dosing. He put me down to start at 2/3mg daily SQ, probably a bit too much to start, however injecting testosterone SQ in the past resulted in much less absorption for me, maybe that is why he wants me to start at...

I think it comes to the delivery method used. Anything that goes to the first pass in the liver or that is applied to the skin could totally have a non physiologic effect, so more like a drug effect. I believe the injection route of administration for Progesterone probably the closet to...

Hi guys, I mentioned in the past that using Pregnenolone cream enhanced my color perception, especially the flashing colors which I would describe almost disturbing. However, when I would generally stop the cream the side effect would disappear within few days. I haven’t used the cream now for...

@Gman86 what was the concentration and base of the injectable Progest? How much did you inject?

Hi Guys, Progest-E was formulated by Ray Peat, it is combined with Vitamin E, and should by pass the first pass in the liver. I'm wondering if anyone has tried this before. To my knowledge this is the only oral Progesterone product that skip that first pass in the liver Dr. Peat's Progest E...

Since we are talking about Progesterone here, has anyone tried a Product called Progest E? I have been looking into Ray Peat’s work, and he mentioned about this product which is Progesterone mixed with some vitamin E, which according to him would by pass the first pass in the liver, therefore...

@Gman86 we chatted before about Iodine, I’m currently using 250mcg only, I believe if someone wanted to supplement with it, 250mcg to 1mg max of Potassium Iodide may be k

Your low ferritin stands out here. Blood donations?

Thyroid hormone helps to convert cholesterol into Pregnenolone, maybe that helped to some extent, did you cholesterol decreased as well?

Are you still using HCG?

I used to, but considering it again since for some reason I have been starting having some trouble with the Pregnenolone for the past year or so, not sure why.

You not longer use Prog? What do you do now to raise Prog levels?

We will see. I’m going to try a new mask see if it improves my SpO2 and RBC

I believe they have resolved the charging issue, 7min charge now can last for 8hr, or something like that I was told at the Apple Store.

@Blackhawk I bought a Sp02 monitor on Amazon and I’m generally have anything from 2 to about 5 drops per night to 91% oxygen saturation. Not concerning as far as sleep apnea I believe, but possibly just enough for the TRT to give more chance to the body to make more RBC. My HR doesn’t even...

What do you think about an Apple Watch? I’m thinking to get a new one, it does also record Sp02, HR and body temp. I believe the upcoming one may have a blood glucose monitor as well

an update here, the 100IU day are still working for test atrophy, calm feeling and some energy I believe. The start at 150IU was really crazy, this is way better. I may try 125IU later on

thanks, this is good info. You just convinced me to buy a SPO2 sleep meter. It makes me think the new CPAP could have made things worse then for me as well, the SPO2 meter will tell. I really started to see the RBC going up since the new machine

This is interesting, thanks for posting. I really would have thought the more Test the more the RBC goes up. We can see how above 50mg things get a little nastier, just where we may get into a supraphysiological dosing. One thing I want to point out, I heard this from Nelson the first-time...

I don't, I use an apple watch though. Although mine doesn't show the oxygen level, I can see the HR which never rise more than about 60, then there is a respiration rate report, which is normal. Years ago when I was diagnosed with a mild sleep apnea, I believe my HR would rise at about 80/90...

When I donated I was at 40mg less of my dose, my body should have replaced red blood cell at a lesser degree already. Plus the additional 14mg dose reduction 3 months ago. We will see, Luckly I have enough ferritin and can donate some blood

The reason I started to lower my dose was indeed to get closer to physiologic dosing of Test CYP My levels were never too high though, even at 140mg on EOD protocol TT at 700 with FT at 26 ng/dl (equilibrium ultrafiltration). 126mg weekly on EOD, TT at 500 and unfortunately, I didn't get back...