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may I know what are your SHBG and E2 values for reference? - Not that I am chasing #s, but it would give me some confidence knowing for example that your E2 is higher than your SHBG and you still feel good (energy, sex drive, etc..)

Thanks, I may do that. I am a low SHBG, so nut sure I can tolerate much E2 but haven't tried for a solid 6 weeks to see how I feel.

Thanks, I should have clarified, I am always with low/high E2 symptoms. So feeling like shit, no libido, anxiety... dark circles under yes, etc... I have yet to identify a symptom that it is ONLY low E2 or HIGH E2... :(. When I feel ok (like 10% of the time), I don't get such effect with...

140mg x week test cip, split into 2 shots, with 0.50mg anaztrozole 24hrs after injection. My SHBG is around 12-13..

I have been trying to dial in my right protocol, but so far not very good results from energy/libido standpoint. When I drink something with caffeine, Instead of getting more energy/alertness, I feel worse like less than 5min after I took it. Has someone experienced that? does someone know what...

Hi, is there any benefit in trying to have a steady daily anastrozole dose vs twice a week?

It is the E2!!! that happens to me when I am "close" but not quite there with my E2.. it could be E2 slightly higher or slightly lower than what you need.

well well, to be honest I have also dropped AI at times and my E2 goes up to like 35-40.. which is super high for me, and I feel reasonably well energy wise and everything. It is just my libido is non-existent. But I have never let it that high for more than 3-4 weeks. So I may give it another...

also, anybody on the calculator?

that is very weird...but it may be the result that everybody is just different. have you feel better with E2 at lower levels like 40-50 or even lower?

not talking about the blood test, I know I can get that, but a calculator similar to the one used to calculate free testosterone. If so, can anyone post the link? I have tried to find it with no luck. I have low SHBG and my E2 needs to be managed at very low levels, so this tool may be useful...

Hi systemlord, I have seen you been posting about low SHBG. Have you found a level of SHBG and E2 in which you feel fine too? - I feel the lower the SHBG, the shorter the time you can keep a proper balance before E2 gets too high or too low again.

Hi, I am a low SHBG guy who has managed to increased it to around 14-15 while on TRT. It has been years trying to fine tune my protocol and after several lab tests and anaztrozole dosing, I have confirmed I feel best when my E2 is around 10ish. At that level my libido is very good, no bloating...

Hi, I am a low SHBG guy and after trying for a few years with multiple dosage of anaztrozole with mixed results, I decided to try the vodka method. So now I take around 0.12 daily with T shots 3 times a week at mornings. But I am trying to decide whether is best to take anaztrozole at morning...

Hello, I have a few years on TRT with very low success. I am also a low SHBG guy. But I just realized I had high TBG thyroid antibodies. I have TSH a little high but T3 and T4 normal levels. The Dr. started me on Levothyroxine, so I am hoping that increases my SHBG a bit. Do you guys think I...

Hi Everyone, went to a new clinic and they put me on 180mg T a week split in 2 doses. they told me they try to shoot for low point to be 1,000 T (so I assume I fluctuate between 1,000 and 1,400 or so). I know this is HIGH, I felt great for a few weeks. Can anyone who maintains high levels of...

Hi Forum, I went to a highly recognized Men's Clinic in Oregon. I am a 32years old male, low SHBG (14-16). and diagnosed Secondary Hypogonadism. Been on different protocols past 2 years with no luck. So The new one is: T Cyp 2x 90mg each (Total 180mg week). HCG 500 IUs 2x Week (Fertility big...

I wanted to have a backup plan in case it does not work with Defy or Dr Chrisler. So after I tried those, I would travel anywhere where there is a well recognized TRT clinic.

Hello, Are labs on DHT accurate/meaningful? - And also, If I am low, and I rub the regular cypionate oil into my scrotum, will my DHT increase as a result? - I know it is not ideal, but right now is the only thing I have on hand.

Haha, ok I guess no one :)

Thanks madman, all what you said makes perfect sense. I am also trying to get leaner and increase physical activity. do we know what drives that initial high? and is it really impossible to achieve it? - I am not even feeling "Ok" at this point, but just out of curiosity.

Hi there, what are the world leading TRT clinics in the world? I am most familiar with options in the US such as Defy and Dr Chrisler, but are there others that are well recognized as cutting edge on this area either in the US or in elsewhere in the World?

Thanks Vitamin C, this gives me hope. I took it at 17-18 years and I also dont recall having a super strong libido before it, but I did feel a negative change after a few years. Maybe it was not the accutane maybe it was something else, it is just that that thing is a strong suspect. I now have...

Thanks guys, for me it worked really well initially.. but apparently that was after YEARS of having low T without even knowing. then it just stopped. Now it is working sometimes but still on trial-error stage with E2.

Is it possible that TRT is not working for me due to the fact that I had my srewed up my Androgen Receptors due to previous drug such as Accutane? I heard Finasteride also creates a similar effect. Any previous users of such drugs with success stories on TRT?

Trying to see if that was the culprit for my low SHBG and Low T issues. Since the Drs never found out what was the cause.

especially for the ones that get T shots every day or EOD. Since Testosterone is very thick not sure it would work though. Any inputs would be much appreciated. I never heard anyone commenting that method in the forum so I assume it just does not work. But if anyone has any experience or can...

Well actually, where the 10 days came from. I know half life is about 48 hours. Will the 10 days thing apply whether I am doing ED vs EOD for example?

Ok thanks guys, that is a great insight. And Vince yeah you are right I should also run labs to see where I am at.

Ok yeah, I guess my struggle is that, say I get my T shot (2x a week). then I get my anaztrozole (say 0.25mg) either 12 or 24 hours after T shot. then I wait a few days and feel no different. I just don't know if I took too much because maybe I crashed my E2 or maybe too little. There have been...

Thanks nurselyfe, this seems to support my hypothesis that although anaztrozole starts doing its thing immediately, there is a certain amount on time in which your existing estrogen needs to be excreted.