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Thorne w/ CoQ-10

I also find libido in the fluctuations - for instance a surge a day or so after injecting HCG. The longer I do TRT, I’m not fully convinced that stable hormone levels are the key to strong libido. There is something to be said for the swings.

Just an update to my initial post. With my doctor’s counsel we’ve upped to 3mg daily as I have experienced no meaningful side effects, BP is under control and I’m trying to see if there is dose-specific improvement to my situation. The other thing I’d add is there seems to be a very mild (but...

Only sides I’ve noticed are slightly less powerful orgasms and lack of urgency to urinate (not necessarily a bad thing, but can be if you wait too long).

2mg daily and no weight gain

Dr. Saya - can you provide insight into the specific mechanism of action for doxazosin? How does it achieve the desired results I’m seeing? I’m trying to understand why my body needs this magnitude of assistance when I’m only 33, active, low body fat, etc. I know it’s a BP med - I began...

2mg in the AM

Need labs. FWIW - I’ve often found hot flashes are a result of E2 moving up or down (e.g. it’s the movement, not the absolute value, that causes it... for me at least). Your protocol may be causing too many swings... not sure until we see labs.

I have a pituitary tumor that has created a multitude of downstream issues that we’ve been addressing successfully in a very methodical manner. This has taken time and discipline on both my part and that of my physician. I simply wanted to share the positive effects I’ve experienced with the...

I also forgot to mention that the entire time, I’ve been on Cialis 5mg daily, which seemed to be effective early on but began to wane over time.

I take the 2mg in the morning. I don’t have insomnia but my dreams have gotten a bit more vivid. Not so much that I would even complain about it (and I’m not even sure there’s a correlation). No BP issues that I’m aware of. The dose isn’t high enough to affect my BP as it’s stayed constant...

I have been on a stable TRT protocol administered by one of the more reputable physicians often mentioned on this forum, but have been chasing ED issues since the beginning. Most recently, I was having issues getting physically aroused, and would lose my erection during intercourse, which is...

You mention weak erections. I personally have found a strong linkage between my fear of erectile issues and low libido. Makes sense when you think about it - why would you allow yourself to want something (or crave it) if you didn’t think you could perform... That said - are morning erections...

I know this thread is a few months old but I am glad to see this post. I have been on a stable TRT protocol for quite some time but have recently been experiencing ED (and lack of morning/nocturnal erections) despite no changes to my protocol, which includes 5mg daily Cialis. My 6 month labs...

My personal experience tells me that T/E2 ratio, not just absolute values, does very much matter in terms of my symptoms.

Thanks! I will check them out now. What about Labrada Nutrition? Any experience with those guys?

I’ve used EAS Myoplex over the years as a meal replacement, mainly for lunches where I can’t get away from my desk. I just found out that it’s been recently discontinued, and am looking for suitable replacements. Any suggestions? I liked how the Myoplex formula was well-balanced, including...

Let us know how this goes! His T levels in the previous labs were truly abysmal, so I’m hoping this therapy will be revolutionary (for you both). As others have posted, make sure you stick to the plan and give it time to work. You are making fundamental (and good!) changes to the body’s basic...

Your T/E2 ratio is low, IMO (meaning E2 too high relative to T). I’ve found if that ratio isn’t finely tuned, it can really offset the subjective benefits of TRT (libido, sense of well being, energy, etc.), ESPECIALLY in a low SHBG guy. It’s different for everyone, but I’ve found that with a T...

Are you on an AI like anastrozole? Sensitivity/orgasm issues for me has always been more related to LOW E2 than HIGH...

Really encourage you to get that sleep study done and report back here with results. Sleep apnea can kill testosterone levels and libido as well. Please let us know!

In my experience, there is no worse ED ever (even before I was on TRT at all) than when E2 is too low. No amount of Viagra or Cialis works for me in this scenario.

Appreciate this article. I have been wondering the same recently as my TRT is very much dialed in, but libido seems to be a dodging target. I’ve noticed that when I let E2 rise a bit by delaying a dose here or there of my very low dose AI (0.07 anastrozole ED), I will have a couple of days of...

Did you just start TRT? A true allergic reaction aside (if you think that's the case absolutely mention to doctor), sometimes it takes time for your body to adjust to the oil. I remember having issues for a couple of months after starting injections and then it adjusted.

I agree - try to go caffeine free for a few weeks and see what it looks like (if this is the cause you may see improvement even quicker than that). Assume you are tracking your pulse often throughout the day via a device, Apple Watch or something? Sometimes just the momentary anxiety of...

If you are at 5.4 for E2, that is 100% why you have erectile issues. The worst sexual dysfunction I have ever had is when E2 is too low.

The issue IMO is their recent change to this "shopping cart" style ordering system. The first issue is that you have to make sure to select the correct med or blood test...there is no front-end validation that you are selecting the right item unless you call prior and get the item numbers (which...

For those of you taking high-dose Niacin (or extended-release Niaspan), have you experienced acid reflux as a side effect? I was recently diagnosed with "reflux laryngitis" after complaining of throat swelling and hoarseness throughout the day, and when the ENT scoped my throat she saw a ton of...

Rising E2 makes me feel generally heat intolerant as well as flushed out. Tons of sweating also.

Thanks for replying Dr. Saya. I definitely appreciate the power psychology can have on all of this stuff and am open to that being a factor here as it has been throughout my journey. My concern here is that something seems to have significantly changed despite a very stable...

Thanks for the reply. I'm open to it being psychological but the strange thing is (1) my libido is acceptable and (2) the lack of penile sensitivity doesn't feel psychological upon first glance. It is like I can't feel the stimulation after the initial erection is achieved, which may be why I...