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The study above though is relating to people on trt - a reduction in LDL levels in those on trt only with higher vit d levels was one finding

https://www.mdpi.com/2072-6643/17/6/1013 Conclusions: The study results suggest that the cardiometabolic effects of exogenous testosterone in men with testosterone deficiency may be determined by vitamin D status.

Totally agree with you about serotonin. Years ago, my gp at the time prescribed me an ssri (paroxetine) when i said i was having trouble sleeping due to stress. "You'll feel great too" he told me..... Second worse med i've ever taken (i binned them after a few weeks) - only one worse than that...

Just realised the email info also opens up on the web - https://chrismasterjohnphd.substack.com/p/methylene-blue-on-the-airplane?utm_source=post-email-title&publication_id=752142&post_id=161243673&utm_campaign=email-post-title&isFreemail=true&r=1d69zf&triedRedirect=true&utm_medium=email

What a coincidence - i was reading this thread earlier today. @Guided_by_Voices mentioned Chris Masterjohn a couple of posts above, who i follow and get emails from. And just now, he's sent out a really long email all about methylene blue. I can copy/paste it if anyone's interested, it's long...

Blimey, that's a bit scary to be honest. It's great the way it comes back with answers in a conversational way, like chatting to a friend. Just it's one of those friends that aren't as bright as they think!!

I gave chatgpt the link to your site, asked it to read what's there, then give me an easy to understand summary instructing how to raise ferritin on trt. This is what it came back with..... ChatGPT said: Testosterone Replacement Therapy (TRT) can lead to erythrocytosis, a condition...

Thanks for that, some great info there. I actually already do some of it (been a supplement junkie since childhood) - i take around 600mg of magnesium a day (glycinate / malate / citrate combo), currently 10,000iu vit d3, vit k2 (mk7 plus mk4), 200iu mixed tocopherols, cod liver oil for vitA...

I'm actually having to go in tomorrow for a blood test and to have my blood pressure taken. They've been texting me for the past two weeks to book myself in, but because i ignored them, yesterdays text said they couldn't issue my next prescription until i've had it done (i'm on ramipril for...

No idea tbh, i don't think i'd take dietary advice from any of the doctors from my gp surgery though. For starters, most of them are obese. Recently, after trying to peddle their statins on me due to slightly elevated cholesterol (i refused them), i was asked about my diet. I mentioned i eat...

Having just read through (most of) this, i thought i'd ask chatgpt about ferritin levels and thyroid. Gotta say, it's good fun using AI, (although i do know the answers to questions aren't always right). You said: Do ferritin levels affect thyroid? ChatGPT said: Yes, ferritin levels can affect...

https://www.sciencedirect.com/science/article/abs/pii/S0899900722000867 Quote: Highlights • Improving magnesium and vitamin D status concomitantly in the overweight or obese population may lead to greater improvements in cardiometabolic outcomes than vitamin D supplements alone • Participants...

https://pmc.ncbi.nlm.nih.gov/articles/PMC7861592/#:~:text=Magnesium%20is%20Required%20to%20Activate%20vitamin%20d&text=Thus%2C%20optimal%20magnesium%20status%20is%20required%20for%20optimal%20vitamin%20D%20status.&text=Both%20magnesium%20and%20vitamin%20D,necessary%20to%20activate%20vitamin%20D...

Any updates on this yet?

I've vaped a small amount of weed (indica dominant) before bed for a few years now. Great sleep aid in my opinion, as long as i don't have too much. In the past i've used ghb for the same reason, but that's not an option anymore unfortunately.

I was getting hct readings like yours, until i realised i hadn't drank enough fluids before blood tests (as i didn't want to be bursting for the loo on the way to the hospital). I was regularly getting hct readings of 0.51 (51%), but after drinking more before going, readings now come back much...

No, i can't understand why some men get married more than once. If a relationship's strong, why should it need a legal contract? I think if you're planning a family, it's a good idea. But if you've done all that, and then the relationship's ended, don't get burnt twice! As to your sex dilemma...

Sorry for also 'highjacking' OP's thread, but the sexually non-responsive partner subject is just too important not to comment on. As far as i'm concerned, when you marry, you take a vow to be in a monogamous relationship with your wife (or husband). What you DON'T sign up for though, is to be...

I don't think it's added to water in all areas of the UK, but where i am (West Midlands) it definitely is. I didn't realise that the tap water in the USA had fluoride added to it too, but according to wikipedia it does: https://en.m.wikipedia.org/wiki/Water_fluoridation_by_country

Thankfully we all have a choice when it comes to salt (unless you live on packaged meals or take aways). I'm more bothered by the fluoride added to our water system here in the UK. The Britta filter i use won't remove that, and reverse osmosis filter systems are very expensive.

All i know is that if i have a very intensive workout and i've sweated a lot, if i don't take extra salt with my water, i'll be getting cramps later on. There's nothing like waking up at 3am with cramp in a calf, throwing yourself out of bed, then getting another cramp in the thigh. This was a...

Yeah, bit confusing that! "1 - 5 pumps", which is it, lol!!

Hmm, that looks interesting. Please update if you decide to try it.

Not that i can find, no. I noticed iherb uk does dhea cream though. Again, not cheap, at least this one tells you how much is in it though (15mg dhea per 1/4 teaspoon) https://uk.iherb.com/pr/emerita-dhea-balancing-cream-with-vitamin-e-fragrance-free-4-oz-112-g/85877

Is that a 3.5 day trough reading Nelson? If so, do you get any problems with raised hct/hgb?

https://unrealsupps.co.uk/iconic-formulations/dermacrine/?srsltid=AfmBOooGfJ6heKOuFm2tAbA2C0bi_BGbnsserUOAiW3IvGEx-KXYMnvH Got dhea & pregnenolone in it, although i can't find out exactly how much. Also, not cheap. I've been debating getting some myself, but i'm not sure i want to spend that...

Just wondering if anyone on the forum has experience with topical androsterone? I'm looking at buying a product (Alpha Gains 1-Andro TD) that contains 100mg of androsterone per ml. I'm looking to try it for its purported mental benefits. Wikipedia claims androsterone acts as a PAM of the GABAA...

Update - since stopping the ipamorelin / mod grf injections, the swelling and itching in my toes has gone. Obviously not a suitable treatment for me.

Rather than start a new thread, i thought i'd put this here. I bought some ipamorelin and modified grf (1-29) just before Christmas, and have been injecting 100mcg of each once a day, monday to friday. Over the last couple of weeks though, i've been getting red, swollen toes. This seems to start...

https://chrismasterjohnphd.substack.com/p/the-ultimate-vitamin-k2-resource

I'm currently taking 12.5mg a day. The ones i have are 25mg tablets, and i just bite half off in the morning when i get up. I hold it under my tongue for a while and let it disolve before swallowing. I don't know where doing this puts my dhea-s levels as it's not included on the Medichecks...