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Thank you for your feedback Leesto. Could you share your experience with Peyronies? Was there anything you could have done differently to avoid it? I noticed on threads from a few years ago that you were very happy with trimix. Do you still feel the same way about it now?

I tried to access this video but it says access denied.

I started TRT about a year and a half ago after being diagnosed with bilateral varicoceles and showing a total T in the low 400's and a free T of 5. I had the varicoceles successfully removed but started TRT because my symptoms were terrible and I was not sure what damage was done by the...

I had a similar experience after being on TRT for 6 months and then adding HCG. I had a jump in Total T around 500 points as well. I reduced my test cyp dose 20% from 100 mg q 3.5 to 80 mg q 3.5 to accommodate that. I inject 150 IU of HCG daily (Crisler protocol). I get my bi monthly draw...

Empower sent 31 gauge needles with the prescription. They seem awfully fragile for the task. I wonder if they will send 29 gauge if I ask.

I would like to start a new trimix thread for those of us who are new to the product. After considerable study (basically reading every thread on excel male going back years) I decided to take the plunge but I am doing so in a conservative and thoughtful way. I was torn between differing...

I posted on this a few weeks ago. I am a high SHBG guy who runs a total E2 in the 50's. I always worried about potential negative effects and even obtained an Rx for anastrozole. Just out of curiosity and caution though I ordered a free estradiol test on discounted labs. It came up right in...

Thank you for your answer Nelson. I will take your advice and hold off on this.

I think I can safely be described as a TRT success story. I am 49 next month and went on TRT after being diagnosed with two massive varicoceles that required surgery. The effect TRT has had on my body composition and overall health have been amazing: body fat percentage dropped from 20% to...

My SHBG runs in the 50's and I inject 80 mg every 3.5 days, 420 IU of HCG M W F and 25 mg DHEA twice a day. I have been on TRT for 15 months and am still making small tweaks to my dose but I am close to my ideal regimen now. It has taken several iterations of making a small change to one...

Thanks Vince. Actually those free estrogen numbers are BEFORE I started the anastrozole so they are the high water mark not the low one. Concur on the dose. It would be nice to see a lot more discussion on here of free estrogen. I am questioning whether total E2 is even relevant.

Here is the embarrassing and potentially catastrophic part. I feel like I have everything dialed in but for my sexual function which if I had to rate I would say is at 90%, lack of sensitivity being my main concern. After addressing everything else the only thing left seemed to be my "high"...

I typically run a sensitive estrogen in the 50's on my labs. My SHBG is also in the 50's. I have been on TRT for about 15 months and the numbers are pretty consistent. I do all the stuff that people caution will spike estrogen: 80 mg test cyp every 3.5 days, 400 IU HCG M W F and DHEA 25 mg...

Also would switching to one injection per week from every 3.5 days have an effect on free E2?

What would be considered a tiny dose of AI? Also how would I time the dose and how many per week. I basically need to tell my doctor what to do and I have seen too many cases of AI overdosing on here. What would be a very conservative way to start?

I did not realize that TT and FT can reduce penis sensitivity. Truth be told I am a little gun-shy on lowering my free T because it was so low when I started TRT, around 5.0, and I did not feel myself and libido was gone. 16 seems awfully close to 5. That being said if lowering FT a little...

I have always run a high estrogen level but I also run a consistently high SHBG. TT - 1010 (264-916) FT - 16 (6.8-21.5) E2 (sensitive) - 40.8 (8.0-35.0) SHBG - 42.6 (16.5-55.9) My last labs were actually low for E2 and SHBG which have both run in the 50's for months, but I have been steadily...

Vince- The range for free T was 6.8-21.5. This was ordered at LabCorp through discounted labs.

I embarked on this journey 14 months ago and rode the roller coaster for months before taking charge of my own health and with the advice on this board and discounted labs finally dialed in my regimen. I see posts on the board all the time from new patients experiencing depression, anxiety...