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  1. Leesto

    Insulin syringe - air bubbles

    I usually get that little bubble too but as Vince said it is negligible in your dosing. Don't sweat the small stuff.
  2. Leesto

    Quad Injection

    I inject into the quads biweekly. No issues other than a sting once in a while but most of them are painless. I use a 27 ga 1/2" needle. Occasionally there's some soreness in the quad the next day but if so it's no different from normal sore muscles: not weird sensations. The grogginess and...
  3. Leesto

    Blood Sugar: Metformin and Berberine

    [/COLOR]Here's an example of a 45 minute workout I do at home about every 4 days. I have very little equipment and no gym membership. If you truly go to failure on most of the sets you'll be wiped out after this and will need several days of recovery. I add weight or slow down the reps each...
  4. Leesto

    New to the Forum With Comfirmed Low T

    Probably many of us started out with big needles. I used a 22 ga 1.5" for many months. What a relief it was to switch to a smaller needle! If you can start out on a smaller needle you'll avoid a lot of the anxiety. I use a 27 ga 1/2" which I find gives a good balance between load time and pain...
  5. Leesto

    Blood Sugar: Metformin and Berberine

    I once had a HbA1c of 13.5. Metformin helped me. Berberine helped me. TRT helped me. But without diet and exercise changes none of them helped enough to matter. The two biggest strides I made against T2 Diabetes were: 1) The ketogenic diet. 2) Intense workouts. Not long workouts, not...
  6. Leesto

    Testosterone and immunity

    I have had no illness whatsoever since starting TRT.
  7. Leesto

    Testosterone and Friendship Formation

    Seems to me that Testosterone REPLACEMENT Therapy doesn't have that effect. You hear about aggression from people on supraphysiological dosages of testosterone but that's not what the folks here are about. Crashed E2 can certainly have an impact on your emotions and mental outlook. Just like...
  8. Leesto

    Blood Sugar: Metformin and Berberine

    Congratulations! I hope you have many more days below 100.
  9. Leesto

    New to the low T and have a dosage quesiton!

    I use Easy Touch 1 ml 27 ga 1/2" syringes and they work just fine. It takes 15 or 20 seconds to load the full 1ml through that small needle and about 10 seconds to inject.
  10. Leesto

    New Poster - erratic T levels

    Here here. I can testify from personal experience that it was a bad starting protocol for me. I was prescribed .25 mg Anastrozole BIW right from the start. I spent a couple months in low E2 hell before I got educated and took charge of my own protocol. Now using no AI at all and feeling pretty...
  11. Leesto

    Cabergoline or Not?

    Just a followup. My prolactin level was 12.1 on December 6th. I started taking 0.25 mg cabergoline BIW. Did not notice much change in libido or orgasm intensity. New labs as of January 31 show prolactin at 1.3! I guess the Cabergoline really knocked it down. I am going to discontinue it.
  12. Leesto

    Hot Flashes and Low E2

    I can tell you that when I had crashed E2 I had hot flashes and night sweats - along with other symptoms. Never when E2 was high. Some people will tell you those come from high E2 but they don't have any good evidence to back that up. I'm sure other members here will pipe up about the symptoms...
  13. Leesto

    Blood Sugar: Metformin and Berberine

    It will be interesting to see the numbers over the next few days.
  14. Leesto

    Blood Sugar: Metformin and Berberine

    The morning dose is without food. Evening is with a late dinner. I have never noticed any gastrointestinal discomfort or other side effects.
  15. Leesto

    Blood Sugar: Metformin and Berberine

    I take 500 mg in the morning and 500 mg at night. That's not a high dosage. Several studies I have seen used 1500 mg per day. From Examine.com:
  16. Leesto

    Blood Sugar: Metformin and Berberine

    I take 1000 mg per day but on most bottles the recommended daily dosage is 1500. Like metformin it can take a few days for it to build up in your system. Since FBG naturally changes from day to day anyway it may take a week or so to identify the degree to which berberine affects your levels...
  17. Leesto

    Starting TRT Soon-Interested in the Way it Has Played Out for Others

    I had a rough start even though I read as much as I could before starting and watched a lot of videos. My doctor started me on what seems to be the cookie-cutter approach with once weekly T injection and twice weekly Anastrozole. Fortunately he also added HCG E3.5D. The first two months nothing...
  18. Leesto

    Orgasms on Trimix

    I have had a similar experience at times. Most of the time I find the trimix delays the climax (which is fine!) but occasionally there is no climax at all. Sex is a complicated process influenced by many factors - the ability to get a good hard erection being just one of them. If the libido...
  19. Leesto

    Blood Sugar: Metformin and Berberine

    I've been taking it for about a year. 1000 mg per day. No side effects that I have been able to notice. FBG drop was around 50. I had already been on Metformin and the keto diet which lowered my FBG to about 190. Adding berberine lowered it to about 140. Further dietary restrictions and some...
  20. Leesto

    Blood Sugar: Metformin and Berberine

    Interesting discussion. I take 1000 mg per day and have been doing so for quite some time. It has helped my blood glucose level and lowered my HbA1C. I have not noticed any side effects at all. That doesn't mean there aren't any, just none that I can notice or identify. I do keep careful notes...
  21. Leesto

    Blood Sugar: Metformin and Berberine

    Another one is Berberine. It has been compared to metformin as to effectiveness. I take 1000 mg per day. It helps to lower my glucose levels and HbA1c. https://examine.com/supplements/berberine/...
  22. Leesto

    Cialis use - Daily vs. higher dose effectivness?

    When we're young and healthy, libido, erection, and climax all go together and just happen naturally. As we age and especially as we depend on medications and supplements and hormones these three aspects of sex can easily get out of balance. Throw in emotional & relationship issues and things...
  23. Leesto

    Daily Cialis Plus Trimix?

    Just an update: I resumed taking 10 mg of Cialis daily (5 mg in the morning, 5 mg at night) as part of Gene's N.O. stack. After a few days on daily cialis I resumed the trimix but at a lower dosage as a precaution. As it turns out, the reduction in trimix dosage wasn't necessary. I have ended up...
  24. Leesto

    Ask The Urologist Anything (Dr Michael Rotman)

    Thank you very much for taking the time to reply!
  25. Leesto

    Ask The Urologist Anything (Dr Michael Rotman)

    Thank you very much for taking the time to reply!
  26. Leesto

    Ask The Urologist Anything (Dr Michael Rotman)

    Welcome DrRotman. I have seen speculation that trimix usage a few times a week for 3 to 6 months can be rehabilitative after a person has experienced many years of ED and no nocturnal or morning erections. I'm wondering if there is evidence of this or if it is just wishful thinking. My doctor...
  27. Leesto

    Ask The Urologist Anything (Dr Michael Rotman)

    Welcome DrRotman. I have seen speculation that trimix usage a few times a week for 3 to 6 months can be rehabilitative after a person has experienced many years of ED and no nocturnal or morning erections. I'm wondering if there is evidence of this or if it is just wishful thinking. My doctor...
  28. Leesto

    Cialis use - Daily vs. higher dose effectivness?

    Spot on. I don't know the reasons, but I too find that early morning workouts are always by far the best ones.
  29. Leesto

    My journey so far with low testosterone.

    This might give you a better summary of the benefits of MCT oil. If you search around the web you'll find a lot of information. There are also a lot of videos on Youtube and a number of books on Amazon.com. But this link will give you a quick summary...
  30. Leesto

    Daily Cialis Plus Trimix?

    Thanks for the info baughts!
  31. Leesto

    Very low estradiol. Boron effect?

    Here's a video that talks about boron's effect on T, SHBG, DHT, etc. I found it interesting. There are some references cited in the footnotes. https://www.youtube.com/watch?v=t124f8rO8XQ
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