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Gman, it's indeed strange that they don't specify the method of testing in the Free E2 results, contrary to the other test results. Looking in the Quest list of tests the only Free Estradiol that I was able to find is test 36169 which is using the sensitive LC/MS measurement. Perhaps the...

I used Gman86's values which he posted above to compare his Free E2 measurement vs. the calculated Free E2 by the spreadsheet. For all of Gman86's tests except for the first one he provided values for both sensitive E2 and NON sensitive E2, so I calculated Free E2 twice for each of test based...

People post here E2 results all the time, usually sensitive E2 essays . They don't refer to it as "total E2" , but that's what they are.

Rafapark & Benm, thanks for your feedback. I replaced the excel file and updated it to .xlsx and it seems fine now. Here's the download link again. Let me know how you like it. Vince, the benefit of the above spreadsheet is to have the Total T and Total E2 adjusted with SHBG and albumin to...

FYI, I just posted a new thread with a spreadsheet to calculate Free E2 based on Total E2, Albumin and SHBG. Welcome to use it!

There's been a lot discussion recently in Excelmale on wanting to test for Free E2 and the relatively high cost of this test. There are online calculators which calculate an estimate of Free T based on Total T, SHBG and Albumin. However there doesn't appear to be an online calculator for...

Dr. Saya, thank you for your feedback!

Is there a formula for calculating Free E2 based on E2, SHBG and Albumin? (There is such a formula for calculating Free T)

As far as I know there are quite a few men with secondary hypogonadism who do well on hcg monotherapy = using hcg stimulation to produce endo T. Thus I don't see why you you regard this as something that shouldn't be attempted.

Dear Dr. Saya, I have secondary Hypogonadism and I've been on TRT for the past three years. My hope is that HcG can cause my testicles to manufacture more Testosterone on their own, so that I can rely less on exogenous T. Prior to reading your study above I was on a protocol for about a year...

That was an old myth. However, there is no point in taking more hcg iu than the amount needed to stimulate your testis. See the following link on how the 500iu dose is much better at stimulating the testes than a 150iu dose: Defy Medical Centers

Low E2 can damage your health, and in particular can cause long term damage to your bone density. The Doctors most often referred to in this forum manage patients according to the sensitive E2 test results, making sure not to lower their E2 too much. If anyone here has references regarding...

I make my own Bacteriostatic Water in order to dilute the HCG. I buy a bottle of USP Benzl Alcohol for 5$ which has a shelf life of up to 2 years and I buy a bunch of sterile vials (25 vials for 30$). I mix in a sterile vile the sterile water for injection which I buy at a local pharmacy...

With your SHBG it's best to inject at least twice a week. Injecting into the fatty tissue in the SUBQ layer causes the testosterone to absorb slower to the bloodstream (in comparison to injecting to the muscle) which is an advantage for low SHBG guys. I inject SUBQ twice a week at my love...

Your numbers look great to me. Ideal E2 is 20-30 pg/ml and you're basically there. Your DHEA is over the high range and IMHO you don't need more DHEA. For many of us ED isn't resolved completely by balancing T+E via TRT. Try Viagra for scheduled sex and daily Tadalafil for unscheduled sex and...

If you have secondary hypogonadism it's best that you take inject 500IU as that dose stimulates your testicles to produce testosterone much more effectively than a 250IU dose. I inject 600IU HCG three times a week. It took a while for my testicles to respond to the HCG, but after a few months at...

I get my Testosterone Enathate in 1ml glass ampules. After I break the ampule open I use a filter needle to draw the Testosterone into five sterile syringes with 0.18ml each which I store in covered with sterile needles with their caps unopened. I use these syringes for my bi-weekly injections...

Hi krm, where I live we also don't have the sensitive LC/MS test for E2, only the ECLIA. What I used to do is aim for E2 in the range of 150-200 pmol/l, which is slightly higher than the upper E2 range for men. This way even if the test is falsely higher, I am still in a good range. And if not...

My protocol is : 45mg testosterone enathate SUBQ twice a week 600iu hcg SUBQ three times a week 0.25mg anastrazole three times a week 50mg DHEA twice a day Teaspoon l-citrulline twice a day 5mg tadalafil once a day plus 25mg slidenafil before planned sex My libido is very high (the dhea has a...

I have low SHBG (around 16) and since I've switched to SUBQ testosterone injections twice a week per Dr Crisler's advice I am able to sustain a steady and healthy level of testosterone and I feel great. Dr. Crisler explained that injecting to the fatty SUBQ tissue causes testosterone to be...

I too am Secondary Hypogonadism I've had similar effects of close to 50% increase in Testosterone levels after I increased the HCG dosage from daily shots of 300IU (2100IU weekly) to 600IU three time a week (1,800U weekly). This jump was not evident in the first month or two after I changed my...

Thanks Vince and AbsolueZ3RO. I don't have the sensitive Estradiol essay available where I live. I considered taking Cabergoline a while back but I was concerned about the side effects and risk of developing DAWS if I needed to stop taking it (DAWS - Dopamine Agonist Withdrawal Syndrome). With...

Hi everyone, I've been reading here for a little over a year and I've found this site most educational. Thank you to Nelson for all the informative material on this website (I also enjoyed your book which I bought on Amazon) and for everyone else here who contributes information and shares...