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Just be careful if you’re low cortisol as more melatonin just makes it worse. I used to take 20-40mg a night and feel better at 0.25mg. I’ve heard good things about the anti aging part of it though.

I don’t like DIM but I’ve admittedly never gave it much of a chance on TRT. If you boys start loving it I’ll consider it. I’ve read things on it being anti thyroid, but since I’m on thyroid meds I don’t know if that’d really matter to me. One thing I have noticed is that guys that say they like...

HCG is documented to do a lot of things. Most of it’s been in women, so that makes it hard to tease some of it out, but it can increase cortisol, E2, 5AR, pregnenolone, testosterone, all kinds of things, and is frequently hypothesized to stimulate the thyroid gland. With how many things it can...

With many HCG mixtures, .1ml would amount to 100iu’s. I used to do that. It’s actually a pretty normal dose on a week to week basis. 20mg of test daily is also only 140mg a week, which is about average for daily dose TRT now. Most guys for that do 100-200mg a week and 140’s right in the middle...

I don’t think it’s estrogen, either, but I wouldn’t begrudge anyone from trying a baby dose of an AI to see if it helped with anything. I only know it doesn’t help me because I tried it. I wouldn’t know that if I hadn’t. Like you, I’d also suggest trying to drop or lower HCG first either way...

Do you mean 0.1 mL and not mg?

I also hate DIM. My E2 for most of TRT was a little less than OP’s with no AI. Right now it’s a little under 80. I‘ve tried AI’s for brief periods and it did nothing positive for me. It’s more about the ratio between test and E2. If you still have a good ratio and nothing bad is going on, enjoy...

$5! That’s cheaper than an UGL. Mine’s part of a membership thing but is around $200 for a bottle like that.

What time do you take it? And what time do you take your NDT? I’ve found I do very differently with all this based on when I take it in ways that are independent of food and absorption Issues.

The only thing I’ve ever done recently that raised my lowerish SHBG (25 for years) was taking Ashwagandha with my thyroid meds before bed (levothyroxine). Got it up to 31 on the last test. Free T3 was up from my prior test (3.8ish to 4.4 as I recall) and so was SHBG. T3/Liothyronine never did...

My penile sensitivity goes up when, in no particular order: My free t is lower My E2 is higher (right now it’s around 79) I have more T4 in my system (in my case from levothyroxine) I have smaller T3 hits throughout the morning (6.25-12.5mcg of liothyronine up to 31ishmcg total or more) I use...

I felt better on enanthate over cypionate, but I also had plenty of other things going on at the time. On the same dosing scheme, my numbers were at least different, and free T and E2 were up a lot. Free T is going down now but E2 still a little higher (79). My doc said it’s also possible I had...

For now yeah. I really enjoyed almost every aspect of it but the intestinal cramps it seemingly was causing by having my organs contract too hard and pretty much any time I ate having to poop as T4 was building up in my system was too much. If I could get by with just T3 and have a functioning...

On the dopaminergic front, a lot of the things I’ve had success with are highly related to that, and the ones I haven’t done well with are at times noted to increase serotonin, which is your dopamine is too low isn’t great. Pregnenolone can do a lot related to PFS but has studies showing a...

I also came into this with PFS and I’d been trying PT-141 off and on over the past couple of months. My sperm was like yours with PFS in that it became watery. HCG solved that for me though, and now it’s so thick it starts conversations. The higher my E2, the thicker my sperm seems to get. AI’s...

Finasteride blocks 5AR type 2, not both 1 and 2. Here are the full list of conversions: Cholestenone → 5α-Cholestanone Progesterone → 5α-Dihydroprogesterone 3α-Dihydroprogesterone → Allopregnanolone 3β-Dihydroprogesterone → Isopregnanolone Deoxycorticosterone → 5α-Dihydrodeoxycorticosterone...

I came into all this with PFS. 5AR does a lot more than just turn test to DHT. Plenty of guys are fine with it but the ones that aren’t, like me, are really, really, life alteringly not fine with it in ways that never go back to normal.

Fertility and keeping your balls healthy and sperm protection up. From there, potentially all kinds of mental and full body effects across all the hormonal cascades. For some guys, we feel a lot better on it. For others, they feel a lot worse. If you feel great without it and fertility or coming...

I came in with PFS and HCG probably did more for me than test. I’ve had my E2 and T ratio all over and at least for me it does not appear to be that. PFS folks are noted to have lower allopregnenolone levels in the brain and other issues like that, as well as cortisol issues. HCG for me as far...

I inject daily SubQ but I couldn’t see myself doing that IM. IM does seem to increase absorption of many things though. Some guys around here report higher T levels from IM, and with other compounds, I‘ve known people like a diabetic that accidentally injected his insulin IM over SubQ and had a...

The first doctor I went to actually ignored me and sent in a nurse that didn’t speak English well enough to understand me, then sent me for a blood test I actually wasn’t able to take at the time they sent me, nor did that lab actually do those tests. I just walked out and never came back, got...

Haha, I wish I never had to try anything! I didn’t have much of a choice though. After finasteride and some complications it caused in me, my life wasn’t something most people would describe as livable, and although I did okay through plenty of periods, I didn’t want to have to settle for...

In my case thyroid meds have a direct impact on my erection quality, more than most things. For me I need a good base of T4 going and enough T3 to be well there. Just T3 and it’s not as great. Just T4 and at least the last time I tried it, it’s not even wood. Has to do with my ability to retain...

Actually, looking into it a bit more, selegiline might actually be causing me to cramp from sympathetic vasoconstriction and generally speeding up my intestines too much to absorb things right. Admittedly these sorts of cramps aren’t like the ones I’m used to experiencing with thyroid issues in...

For me it’s definitely not fatigue. I’ll try putting it another way: I typically wouldn’t be compelled to do things like lay down or rest, binge a TV series, get caught up in something fun, understand why people dance to music, or enjoy a view. On Selegiline I do. Even if I was tired my mind...

Quite a few. Thyroid conditions, cortisol being too high, seemingly any nutrient deficiency and malabsorption, gallbladder issues, sleep apnea making your sleep suck, bad reactions to medications like finasteride and others, cancers, various autoimmune disorders, depression. Exercising too much...

It’s definitely not for everyone. Seems like if you have other issues going on and intervene with your hormones, you can make a lot of things worse, which is probably why your body was lowering it’s test to begin with. It was trying to avoid that.

I’ve been on 2.5mg of selegiline in the morning under my tongue for months and love it. Mostly makes me feel like a normal human being probably would. Actually calms me down. I almost fell asleep working just now because what I was doing is something I hate and is braindead work. I’m not the guy...

I definitely have very different reactions to T3 based on when I take it, and in what amount. Generally, little hits in the morning hours or right before waking are more towards stimulating, whereas in the evening it’s the opposite. Matching the daily rhythm of it mattered less than take more...

Right now I keep my salt intake constant and have a very decent amount of it. In the past I got up to 1 1/4 tsp 2-3 times a day with meals when I was at my worst. When I stopped I went to the hospital. I found out at the time I needed more because my cortisol was so low and potassium so high...

I did different variations but they were mostly the same with different substances. I’d either take 20mg of hydrocortisone or 25mg of cortisone acetate per day, divided into the smallest doses I could make (1/8 a tablet as I recall), beginning before I woke up around 6ish when I’d get up to pee...