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I am currently on 200mg per week, but I divide it up into 40mg injections 5x weekly (every weekday). I only did twice weekly injections for a short time when I was on 100mg and as soon as I went to 5x weekly (Mike at Defy’s suggestion), my HCT dropped below 50. It’s actually lower now than when...

I would not take it more than 1-2 times per week, and if you take it twice within a week then space it out to every 3-4 days. The melanocortin receptors become desensitized very quickly, and you will stop feeling the effects with repeated use if taken close together. The good news is that this...

You are inserting words in your defensiveness that no one has used. No one said a pump is the sole answer. But you do suggest them as a solution virtually every time the topic arises. I didn't have to look far.. The world is a lot bigger than ExcelMale, and PeakT for that matter. It is...

Practicality... People are not going to wear insulin / infusion pumps. It isn’t a popular option now even though it is available such as for diabetics unless it is life-sustaining/saving and the patient has no choice. Patients won’t wear their CPAPs. People won’t wear face masks that are free...

Cataceous, I will tell you what these (your) posts are causing. They are causing people to ask for help because they feel horrible not even being able to leave the house after taking Gonadorelin and they are referencing these posts as justification for taking it. They get it from a clinic or...

Gonadorelin may sound good on paper, but will never be an alternative to HCG in the real word. And these posts both promoting it and calling experiments with it “a success” are actually causing harm to people.

The answer to your question is unknown. The closest thing that is commonly associated with the sexual dysfunction/libido side effects is Post Finasteride Syndrome (PFS) - a seemingly irreversible loss which is possibly due to the inhibition of 5-alpha reductase from the drug. There are theories...

No, it wasn’t. Not even with hundreds of mg per week. I feel nothing from T. There is almost no 5-AR happening. The Accutane did something to permanently limit it to almost zero. The drug is a 5-AR inhibitor for anyone who doesn’t know. It didn’t all start until a couple of years after stopping...

I have permanent side effects and I was prescribed 10mg. Accutane is the reason why I’m on TRT. And I’m not making it personal, I’m saying this as matter of fact as possible. This is one of the few times I will say that no one should ever take this drug. By the time problems start years later...

Jesus, never mind the horrible and permanent side effects that isotretinoin is known for like destroying your libido for the rest of your life. You were very lucky. But maybe not, because the onset of side effects is sometimes years after you stop taking it. Anyone thinking about taking...

I personally have not seen HCT go up unless the dose injected is around 50mg or higher.

That is one use, yes. Much of the data comes from use with trauma / burn victims. Oxandrolone has a well-established safety profile, even with children.

madman is right. The c-17’s won’t be prescribed as to be taken indefinitely. Even a very safe low dose Oxandrolone is normally prescribed for longer periods if you have wasting - recovering from surgery or illness/disease or have HIV. And with Stanozolol in particular, it drastically helps if...

Your feeling of well-being is ultimately dependent on your state of mind. Your hormones affect your mood, yes. We also get an increase in dopamine when we start something new such as TRT or when there is a change in protocol. That feeling of excitement and energy and change and hope or whatever...

Nandrolone will lower your Estradiol. It will increase HCT. One of its first uses was to treat anemia. You can however divide your ND into smaller doses and it should not affect HCT as much or possibly not at all. I have seen it in others and in myself. I divide and take it every weekday, so 5...

Testosterone has always done very little for me relatively speaking compared to what I have seen and heard from others. Nandrolone helped with building muscle. Oxandrolone and Stanozolol have helped with losing fat and libido. Not all at the same time of course. Defy can prescribe them. It’s...

There is indeed a correlation. If you don’t have additional body fat to lose then you were likely borderline. You could talk to your doctor about reducing your testosterone dose. No one wants the OSA diagnosis, but if you need a cpap then you need it. Many guys say a cpap is a massive help and...

Just so that you have some realistic expectations, Testosterone will cause hair loss and balding if you have the genetics for it. What that also means in that case is that it is going to happen anyway. The testosterone only accelerates it. So stopping or not, you are still going to have to take...

More than likely it is simple lobbying by industry food groups. “Want to get re-elected? There sure is a lot of corn grown in your state. It would be a shame for all of those jobs to be lost on your watch”. That’s why. The sugar industry did the same thing decades ago to make fats the villain...

I haven’t seen anywhere that the device’s specifications are listed so that anyone can make a comparison. Any device in a clinical setting clearly spells this out in product information and on public web sites. A legitimate product has nothing to hide and the details are important because the...

A machine equivalent to this in a clinical setting has a cost that starts at many, many times more than that device and a minimum of 6-8 sessions would be typically recommended. Orders of magnitude more in cost. So there is your baseline. It may be able to help with a very basic case, but you’re...

Your melanocortin receptors are desensitized from using it too often. It varies person to person but 3 times a week is a lot. Take a 2-week break and then try decreasing use to 1-2 times per week.

I'll try to reply this week when I can. Hormones can fix a lot of problems, but not all of them. Everyone should make their own choice, but for me quitting TRT wasn't ever an option. The restarts don't work most of the time, and it would put one right back at the starting line before all of what...

See my recent reply here. Libido is not as simple as testosterone, or often hormones for that matter.

For what it’s worth, my own battle with libido was for nearly 4 years after starting TRT with a local urologist in a small town and then going to Defy after the urologist basically broke up with me in an email saying that he couldn’t help me and to maybe try “one of those new online clinics”...

Don’t get me wrong, it’s fascinating. I have read the posts. It just isn’t practical in real world use. The pump would help with the dosing since no one is going to inject themselves every 2-3 hours. But there is the problem of cost developing one for this application and then cost to the...

I won’t speak for Dr. Saya, but I have seen a discussion on GnRH involving some compounding pharmacies and gonadorelin specifically, and that it is not a viable alternative to hCG. It is not intended for prolonged use, and patients will end up with a net suppressive effect over time with...

Lp(a), CRP, and Homocysteine are far, far better predictors of CVD than LDL.

I’ve noticed that a lot of the smaller compounding pharmacies are doing that. Maybe they don’t have the equipment to lyophilize the product, or it would increase the expense. I am not too familiar with the products that ship ready to use so I can’t give you much info on them unfortunately. I...

I had been using LE’s DHEA that I always bought on Amazon - same 25mg that I had taken for years keeping me around 500. It shot up to 950. Switched to Douglas Pharmaceuticals and it is back down to 450-500. See my post above. Life Extension is a reputable brand, but what I said applies even...

You may be sometimes close with that 30%. Not trying to sway you either way, but one of the USP specifications applicable to these products is potency and the specification allows for 90-110% - a potential 20% difference between 2 products. It isn’t going to be 1:1 with regard to difference in...