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Yeah. I'm just exhausted from not sleeping well. It's taking a huge toll on me right now. I may get some blood work for iron/ferritin to see if I look low there. One other possibility is that my iron stores were low from the double red donation in October, and then being hypogonadal on the...

Yes, it happened within a few days of starting that got worse the longer I used the Deca. The same thing happened a few times when I used too much progesterone cream on my scrotum a few months ago. However, that issue resolved immediately upon cessation of the progesterone cream, whereas this is...

What I don't understand is why this would have happened suddenly. I never experienced this before the last few weeks and all of a sudden it's come on. I'm quite discouraged as I had been fine for many years and then this cropped up. Did your issues arise suddenly?

The rest of my labs are back in. Everything looks fine except the creatinine level. Free T:E2 ratio looks closer to what Defy wanted to see me at. Sensitive E2: 27.7 pg/mL ref 8.0-35.0 Free Testosterone: 23.2 pg/mL 8.7-25.1 Testosterone: 884 ng/dL 264-916 SHBG: 19.9 nmol/L 16.5-55.9 Sleep is...

Thanks for posting that. I feel a bit better seeing that. I haven’t worked out in 10 days due to a bad cold I’m now getting over. What other values would you want to see to evaluate kidney function? My SHBG is unchanged from when I was on ED propionate. I would expect that it would rise on...

CBC is back along with TT test. Alarmed to see kidney function appears to be affected and was decidedly not the case when I had full labs back in October. Including a few values here for reference. Free T, E2, and CMP are not back yet. October 8 December 30 Hemoglobin 16...

What did your TT, FT, E2, SHBG numbers look like during these periods where you felt so bad? I'm wondering if there is something to be gleaned from your FT:E2 ratio, or your total E2 level being low, or low SHBG, etc. How did your hematocrit and hemoglobin look during the worst phases for you...

How long had you been on TRT before this? What other changes did you make? What type of testosterone were you on (ester? compounded or pharma?)? Were those side effects things you dealt with the whole time on TRT or did they come on after a protocol change? How is your libido, erection quality, etc?

Labs were drawn this afternoon so that’s good. Should have CBC and CMP soon so I’ll know where hematocrit and hemoglobin are along with other basic values and then will wait on TT/FT, SHBG, and E2. I’ll be calling Defy before they close tomorrow to see if the CBC and CMP are in. Tonight is a...

I understand what you’re saying. At the same time, I’ve done my work in therapy and know the difference between what’s in my head and what’s quantifiable. TRT has not been an area that has made me anxious in the past, and I’ve been on for the better part of a decade. The issues that drove me to...

I agree. There’s a difference between “I’m adjusting” and “there are subjective and objective measures of well being and mine are all trending downward the longer I’m on this protocol.” I don’t know if a smaller amount of nandrolone would work but I first want to get back to a baseline of...

I think I’m going back to pharma test anyway. I get my insurance to cover it so I may as well only pay $10 for a 10ml vial if I can.

Keep in mind that it may not raise cortisol in you. Everyone is different and the fact that I may have increased activity at the mineralocorticoid receptor from nandrolone may not show up that way in you. Same reason I have had water retention on moderate doses of testosterone and other guys...

Thanks. I appreciate it. I'll be very curious what the lab work shows. I've been looking into the effects of high cortisol and it sounds like everything I've been experiencing since I went on nandrolone -- frequent urination, digestive trouble (constipation/bloating), disrupted sleep, BP/HR...

Just spoke with the RN at Defy. Her hypothesis is that my hematocrit and hemoglobin might have gone too high, which is causing the eye floaters, elevated HR, etc. She thinks my cortisol might be high as well either as a side effect of disrupted sleep or as a result of some other issue I'm...

I will. The problem is I changed too many variables at once so I don't know what is responsible for these issues. I also think the carrier oil could be an issue. Feeling really down and out about this stuff.

I have still been using the nandrolone at 84mg/week and bumped test a bit. I have a "symptoms" call with Defy in 15 mins to see what the RN thinks. I wanted to try riding it out for 6 weeks based on the feedback from @Vince Carter, @xqfq, @DS3 and others and see if I settled in but I don't know...

As an update, I'm feeling increasingly concerned about my body's reaction to something in this protocol. I don't know if it's the carrier oil or the ester or the nandrolone, but my sleep quality has continued to decline, my resting heart rate has increased, my heart rate variability has...

It’s currently grapeseed. I have been using pharma test with cottonseed for 8 years with no problem. I wonder if I’m the reverse of you. How did you narrow it down to the carrier oil?

DMed you.

I hear you. I'm going to ride it out for a while on this dose and see what happens, especially after this cold clears. God knows being sick can kill the libido and I got some decent nighttime wood last night, so who knows where things actually are. If I don't settle in after 6 weeks to a...

Ah shit. I'm sorry to hear that. I've had cancer myself in the past (a very rare soft-tissue sarcoma). I hope your treatment went well and that you're in a durable remission.

That's absolutely fascinating about your propionate dosing. I wish I'd talked to you before I dropped the propionate. My abdominal bloating got noticeably worse on ED prop but I wonder what would have happened had I tried EOD dosing. My trough was so low on ED dosing that I just didn't think it...

I am definitely worried about cardiovascular issues, as well as a supposition on my side that my libido and erection quality do better when my E2 runs a little higher. On test cypionate I never really had runaway E2 levels like some guys get, so I actually suspect that my water retention issues...

Many, many thanks for this and your prior reply. I know that I've been changing protocols too much and I am going to stick it out for longer on this enanthate/nandrolone protocol to see what happens as I settle in. Message received, and thank you (and others like @xqfq and @Vince Carter as well)...

Thanks for this perspective. My cold has gotten worse so I am thinking that some of what I've been experiencing is due to that, as my sleep has been atrocious due to breathing issues from a cough, nasal congestion, etc. The bounding HR on exertion/standing symptom you had is similar to what...

One additional note. Prior to these recent changes (when on cyp only) my forearms and arms were typically quite vascular. Since starting this protocol my vascularity has noticeably decreased. Not sure if that’s at all relevant.

Fair points. But I guess I’m just freaked out by always feeling these heavy heartbeats. I am 38 and don’t have much interest in having a heart attack.;) I have been struggling to sleep because of this elevated heart rate. I hear what you’re saying about not changing course too fast. I guess I’m...

I’m on nandrolone at Defy’s suggestion to help balance my E2: Free T ratio. I was at around a 2:1 before and the PA at Defy wanted to try getting me to 1:1 without using an AI as I’m not willing to use AIs long term and always felt like garbage when I’ve tried them (both arimidex and...

Glad to have you following along. I’m going to inject tonight with my pharma cyp I have on hand since I know it doesn’t make me react badly. Once I get regulated I’ll try the deca again. If I get the same reaction I’ll try to get deca compounded with cottonseed oil to see definitively if it’s...

Haven’t used progesterone cream for months. No other hormone affecting supplements either. The only other difference is that I switched from pharma test cyp to compounded enanthate with a different carrier oil. I agree that it’s weird the nandrolone would cause this since it’s such a long ester...