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Doc said once in AM.

Actually, I feel good, but am concerned about numbers, meaning T levels 35%-45% lower than pre-treatment and DHT is 2.5X higher, while Estradiol and SHBG are very similar. The conversion to DHT is irreversible. Do DHT levels vary throughout the day like T, which people here are saying I captured...

DHT went from 36 to 95 over same period. Does cream have trough issue if it had been nearly 24 hours since prior application when measuring T (but trough doesn’t apply to DHT levels, or estradiol or SHBG, only T)?

Update on Labs: DHT before T cream: 36 DHT after, lab at same time T measured: 95 So if the issue is trough was measured for Testosterone, is it not same for DHT?1 Or, am I over converting T too much to DHT, which is irreversible?

Excellent question, and I had thought about trough but didn’t think it was parcel to cream application….it had been close to 22 hrs since prior AM application (meaning I applied the prior AM, then had an AM draw the next morning). TY.

Just started TRT, 200mg cream in AM to scrotum 6 weeks ago with 50mg DHEA and 100mg Pregnenolone. At start my labs were, and frankly felt very “good” generally, mild libido issues, wanting to merely optimize overall health and vitality (active 55 YO), all other labs normal/optimal incl Thyroid...

Been on 200mg cream for 6 weeks, 50mg DHEA and 100mg Preg. T has gone from 502 to 187, and Free has dropped commensurately. Estradiol and SHBG stayed same, while my LH has hit the floor. DHT was low normal before and while I’m waiting for that lab to come back I’ll assume it’s high, although I...