Search results

Am I the only one that actually read the study? https://journals.sagepub.com/doi/10.1177/15598276231181574 The plant-based diet did improve the diabetic parameters (probably due to the exclusion of junk food as already stipulated) but not impressively so: A1C dropped to 6.0%, fasting glucose...

The Rosuvastatin reviews are really bad but I don't see studies of actual alternatives that can safely lower CRP inflammation of unclear origin. Colchicine is approved for decreasing CRP and it does decrease risk of cardiovascular events, as expected, but it is an immune suppressing drug...

Aspirin has not been shown to consistently lower CRP in healthy people with elevated CRP, which this thread is about. In those people, often the reason for CRP elevation is not known, so it is not clear how to "reduce inflammation". Aspirin also causes gastrointestinal lesions even at the...

Summary for the less scientifically inclined: https://www.ajmc.com/view/ajmc_10aug_ridker_561to562 In brief, the 18,000-participant JUPITER trial overwhelmingly confirmed (1) that those with elevated hsCRP are at substantially elevated vascular risk despite low LDL-C levels and low Framingham...

A randomized placebo-controlled trial of the anti-inflammatory effect (reduction of C-reactive protein) of 20mg/day Rosuvastatin in the so called JUPITER trial in people with normal LDL, but elevated C-reactive protein: https://www.nejm.org/doi/full/10.1056/NEJMoa0807646 It is interesting to...

Again, is there an actual study in humans, not speculations based on in vitro studies or 20+ pages of broscience gibberish? At your level of intelect, you should already know that in vitro studies and biochemical speculations often do not translate in vivo and that difference should be...

Although Indian studies tend to be less quality than western ones, this study shows that in truly hypogonadal men even restoration to low normal testosterone (370 ng/dL) improves sexual function. This is important to understand for people that have low normal testosterone above that level and...

Nobody has the time to read 20+ pages of gibberish. Link to the study?

In general diabetes with poor blood sugar control drives higher inflammation and hsCRP but your A1C doesn't seem high enough to explain your higher hsCRP. Still the A1C is a marker of the average blood sugar, maybe you have higher peaks. Are you on insulin or just metformin?

What was your HbA1C when your hsCRP was 2-3?

You should be careful with fermented foods because the microbes can drive inflammation too, no matter that they are pictured as "good bacteria". If your immune system finds a problem with them, it won't care how "good" they are. My immune system started recognizing the bacteria in yogurt and I...

Have you ever stopped drinking raw milk which contains inflammatory lactose? Carnivore diet is the most eliminating one and many people reverse type 2 diabetes on it. Blood pressure goes down too.

What is your hsCRP? Do you have health conditions that increase CRP, like chronic infections, diabetes etc? Have you tried full keto or carnivore diets?

You can more safely reduce inflammation and hsCRP by adopting a low carbohydrate diet or at least drop the fast sugars: processed foods, natural fruits, honey, milk These contain glucose, fructose, sucrose (white table sugar), or lactose.

I am less enthusiastic about colchicine. While it decreased mortality from cardiovascular events, it did not decrease the overall mortality (my guess due to increasing mortality from infections). https://www.internationaljournalofcardiology.com/article/S0167-5273(22)01900-3/fulltext Here are...

Colchicine use is helpful for some infections where inflammation needs to be reduced but can increase the probability for other infections: https://europepmc.org/article/MED/33360321

Be careful with the colchicine dose. It easily gets toxic even only because other drugs reduce its clearance or your kidney/liver do not remove it properly: https://en.wikipedia.org/wiki/Colchicine#Drug_interactions The dose they tested is 5mg/day but you can start with half a tablet twice...

With high prolactin and low libido, your PCP should prescribe prolactin. Show them a medical study about it - that will give them more confidence that it is OK to prescribe it in such cases.

I think the authors have signs of dementia or they have not learned anything in med school. Dementia is of course linked to vision and hearing impairments because they are all due to damage of the brain. The "genuises" that wrote the article think that fixing vision will somehow prevent the...

The study for the PDE-5 is not randomized but observational. It cannot prove cause and effect because the groups being compared are not randomized/balanced on all the other variables that can affect the outcome. That's why they say it needs to be validated in a controlled clinical trial. As I...

This is not what the study can claim. It is again not randomized so you don't know what groups are actually being compared. They "matched" the patients in the diabetic metformin group to the non-diabetic non-metformin group. This is not randomization. I suspect a diabetes type 2 patient was in...

The obvious question is why someone with erectile dysfunction did not take a PDE-5i drug. Possibly, they tried it but it didn't work (suggesting they have a more substantial cardiovascular damage) or they were not interested in sex (suggesting they were more sick). The lack of randomization...

Metformin should work in diabetes 2 because it reduces blood glucose but failed to make a difference in long term diabetes 1 (which was the only randomized trial in the review). It is also currently lacking randomized trials for reducing heart attacks and strokes - supposedly will be finished by...

It's not the cholesterol stupid, it's the inflammation! Low dose colchicine (an anti-inflammatory drug for Gout) is approved for reducing the risk after heart attack or stroke. I bet it will help prevent arteriosclerosis which is caused by inflammation from eating too much carbs/sugar...

No sane doctor will prescribe you testosterone because your testosterone is completely healthy level and does not explain your lack of libido at all. Doctors cannot prescribe drugs at a whim. It is also not "decreased" as you claim because a change from 14 to 13 is just a normal daily...

Minoxidil can also have sexual side effects.

If you are on a low carb diet, like carnivore, you may be a "hyper responder" who has a high LDL to the diet. This poses no risk for cardiovascular disease and statin is completely not warranted.

A drug can damage you later doesn't matter it was fine initially. Oil soluble statins reach the brain and are suspected to increase the chances of dementia. Seroquel is definitely a libido killer by decreasing the action of dopamine. Ozempic can reduce libido.

The truth is they are only guessing that statins affect libido by "lowering testosterone" and it is the most stupid guess possible because they think libido = testosterone, while in reality libido is governed by gazilion factors outside testosterone. Your triglicerides are low excellent which...

I suggest you try to achieve health in a natural way through the natural food you eat and a healthy lifestyle, not with drugs, vitamins, or unnatural supplements. Then, you may regain your libido. It is not reasonable to expect your body to function in a natural way when you take a bunch of...

https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/ask-the-experts/statins-and-sex