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    Anyone supplement E2 alongside TRT

    What is your injection frequency and when to you test levels relative to injections? Physiological TRT doses are more like 40-90 mg TC per week in divided doses.
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    Lowering Test Cyp Dosage - Can't Sleep And Irritated

    Then there's this one we discussed previously: https://www.ahajournals.org/doi/full/10.1161/HYPERTENSIONAHA.119.12780 Excessive erythrocytosis (EE; hemoglobin concentration [Hb] ≥21 g/dL in adult males) is associated with increased cardiovascular risk in highlander Andeans. ... Hyperviscosity...
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    Lowering Test Cyp Dosage - Can't Sleep And Irritated

    I made a similar discovery regarding testosterone and sleep, and I take a similar amount of testosterone, equivalent to 44 mg testosterone cypionate (TC)/week. If you're inclined to experiment then you can possibly benefit by introducing diurnal variation to your protocol. While injecting TC...
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    Anyone supplement E2 alongside TRT

    Anecdotally, some guys see improvements when reducing testosterone to more realistic levels. Even 80 mg TC/week combined with hCG is fairly high compared to what's natural. However, if my experience is also broadly applicable then the problem is not necessarily something that can be fixed by...
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    Absolute minimum dose of HCG for fertility?

    It's just anecdotal, but reports suggest that dosing hCG as low as 250 IU twice a week still can yield benefits.
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    How long after the "best use date" (BUD) does T cyp/prop retain its full efficacy?

    Manufacturers usually recommend against refrigeration as this can result in crystallization. This doesn't cause permanent damage to the product, but if this happens it must be properly warmed to put the testosterone ester back in solution. I suspect that cooling wouldn't provide much additional...
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    Testosterone Propionate

    If you want to be spared then head off to a forum where discussions of such cycles are encouraged. This isn't the place for it. Taking 280 mg/week TP has little to do with TRT and men's health.
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    Allergic to cotton seed oil

    Switch to testosterone enanthate. It's basically interchangeable with testosterone cypionate, and the commercial formulations typically use sesame oil. One manufacturer is Hikma Pharmaceuticals.
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    Last Throw of the Dice - advise on Arimidex dosage

    I think I would start with a drop to 20 mg per injection and give it at least two months. If things seem to be going in the right direction then you could try the lower dose. With the dominance of longer esters in Sustanon you can't go as low on the dosing as you could when using a blend high in...
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    Last Throw of the Dice - advise on Arimidex dosage

    In reality 75 mg TC/week is a middling-to-high dose relative to normal physiology. You could cut your dose by 30+% and still have higher numbers than the average healthy young guy from 30 years ago. I would experiment with lower doses if you continue to have problems in spite of changes in diet...
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    Discouraged with TRT continuation part 2

    The subject is thyroid hormones and the best you can do is some handwaving about testosterone and breast cancer? It's a roundabout way of saying that correlation doesn't establish causality. But you conveniently ignore the animal studies, which are interventional and support the premise. Also in...
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    Discouraged with TRT continuation part 2

    There's a lot more than the one study supporting the premise that higher thyroid hormone levels reduce longevity. For example, I cited other studies here: A recent large study by Collet et al. pooled individual data from 10 prospective cohort studies and concluded that endogenous subclinical...
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    Less than 50 mg of T per week

    I am a proponent of using the lowest effective dose, and I do well on the equivalent of 44 mg testosterone cypionate per week. However, I take my testosterone as daily injections of a propionate/enanthate blend. Although my average serum testosterone is around 500 ng/dL, daily peak levels are...
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    Lowering Test Cyp Dosage - Can't Sleep And Irritated

    You were thoroughly acclimated to taking roughly twice as much testosterone as you would make naturally at your best. It's no surprise that the withdrawal is taking time. For encouragement, read what @Simbarn says about weaning off of higher doses:
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