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    Help determining proper pregnenolone dosage and frequency

    You are very welcome! You can try low dose of transdermal pregnenolone appied E3D or E4D. Trandermal application stays up to 5 days inside skin. If suspended in DMSO even longer.
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    Help determining proper pregnenolone dosage and frequency

    I think you have such a effect with different doses because of Pregenenolone u-shape action Biphasic, U-shaped actions at the GABAa receptor
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    Navel transdermal testosterone

    Yes, I've tried scrotal testosterone dissolved in 10% DMSO and worked very well but caused testicular pain so I had to stop.
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    Pregnenolone 101: What You Need to Know About this Precursor Hormone

    Sublingual- very short acting ,effects like pure sublingual progesterone, put me too sleep and made groggy next day
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    Pregnenolone 101: What You Need to Know About this Precursor Hormone

    I've tried orally, transdermally and sublingually. Transdermally works the best for me.
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    Pregnenolone 101: What You Need to Know About this Precursor Hormone

    I think pregnenolone shouldn't cause gyno problems especially in physiological doses 30mg-50mg transdermally daily.
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    Navel transdermal testosterone

    Has anyone tried navel transdermal testosterone application? This study Navel absorption: transdermal bioavailability of testosterone shows bioavailability of 79.9% compared to 49.9% forearm administration.
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    No Libido

    What's you body temp in the morning? Mine is caused by hypothyrodism. In that condition body compensate for energy pumping high adrenaline. For tigh cremasteric muscle try reverse kegels.
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    Increased bright colors perception on Pregnenolone?

    On topical pregnenolone I feel like on shrooms micro dosing. Effects are bright, vivid colors with more contrast and my hearing is more sensitive as well. So pregnenolone definitely increase senses.
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    No Libido

    Thight scotum indicate high adrenaline or high stress response
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    Anyone tried testosterone base (no ester)?

    Will oral micronized Testosterone base work for TRT? If yes, what dose?
  12. N

    Dht levels

    I think scrotal application is the best bang for the buck cause of highest absorbability for the amount used especially when mixed with DMSO.
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    Dht levels

    Please read this thread Pharmacokinetics of testosterone cream applied to scrotal skin. There is a study with graph showing that DHT will stay long time elevated then Testosterone after aplication.
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    Achy , tensed feeling muscles a side effect

    More fat you carry more Estrogen will convert from Testosterone. Try to lower dose to 10-15mg ED or switch to test cream and see how you feel. If you apply Test cream to scrotum most of it converts to DHT and little to Estrogen.
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    Achy , tensed feeling muscles a side effect

    I have this feeling when my E2 is very high. Are you bloated (water retension)?
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    Achy , tensed feeling muscles a side effect

    Do you feel muscle tension? How is your diet and sleep?
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    Development of neuroactive steroids for the treatment of postpartum depression

    i noticed It builds up after daily use due to longer half life in skin. Skin works like reservoir.
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    Development of neuroactive steroids for the treatment of postpartum depression

    Same thing, even 1mg on balls before sleep give me deep and restful sleep. Applied at daytime on the other hand makes very calm but fatigued and slow.
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    Progesterone in Men

    On what part of the body are you applying the cream?
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    DOES MELATONIN MAKE SEX FEEL BETTER?

    Another benefit of melatonin is that inhibits and downregulate aromatase activity.
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    Estradiol and Social Anxiety

    Daily 30 mins meditation resets dopamine receptors and whole nervous system as well.
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    Estradiol and Social Anxiety

    Have you tried topical testosterone? Works 100x better then proviron
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    Estradiol and Social Anxiety

    Progesterone act like natural benzo so it should help you with anxiety and calm you down. You have to play with dosage though too much it wakes me up so start low. Progesterone cream also builds up into skin making very long half life, sublingual works shorter but stronger in my experience.
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    Estradiol and Social Anxiety

    In the past I've tried SSRIs, benzodiazepines, betablockers, herbs and felt felt numb and indifferent. The only herb what worked very well was St John's wort (natural SSNRI) but also had side effects like photo sensitivity and insomnia. Additionally I only take progesterone before sleep...
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    Estradiol and Social Anxiety

    I agree with you is very powerful androgen. Im using only 1mg trans scrotal daily anything more makes me too relaxed and lazy.
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    Estradiol and Social Anxiety

    I am using androsterone it lowers estrogen, its gaba antagonist and raises DHT. It works very well for my social anxiety.
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    Estradiol and Social Anxiety

    Individuals with SAD have higher serotonin not lower Individuals with social phobia have too much serotonin -- not too little Cause: Low or high E2 Symptoms: No difference in my social anxiety, higher E2 racing mind and more libido, lower E2 better cognition less water retention, very low E2...
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