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The study described in this article found a lower risk of prostate cancer in men on testosterone therapy. "We conducted a study assess whether testosterone therapy (TT) alters prostate cancer risk using a large US commercial insurance research database. From the HealthCore Integrated Research...

This is the relevant text from the financial news article: India’s largest drugmaker Sun Pharmaceutical Industries has recalled testosterone cypionate for injection in the US, data on US Food and Drug Administration (FDA) website released Wednesday showed. Testosterone cypionate, used to treat...

Recent news articles have claimed that there is no good evidence of cognitive benefits from testosterone therapy. However, a recent meta-analysis found "strong evidence" of benefit. The study is described in a news article in Medical Express: Taking testosterone supplements can boost men's...

The question often gets asked why testosterone levels are decreasing. It looks like water fluoridation may be part of the explanation. The study title is "Associations of fluoride exposure with sex steroid hormones among U.S. children and adolescents". The abstract says: "Fluoride mediated...

A press release describes a study that found a high fat meal (any kind of fat) lowers testosterone levels, while a high protein meal (egg white or whey) raises them over the following five hours. This goes against the usual advice I see on the Internet that you should "eat healthy fats" to raise...

A new study reaffirms the benefits of TRT, at least among opioid users. The article says: There may be mortality, musculoskeletal and cardiovascular benefits from testosterone therapy among men with low testosterone due to opioid use, according to findings published in JAMA Network Open. Jasuja...

Another study finds increased risk of kidney stones. The abstract says: We conducted a population-based matched cohort study utilizing data sourced from the Military Health System Data Repository (a large military-based database that includes beneficiaries of the TRICARE program). This included...

Tlando is an oral form of testosterone undecanoate and failed to achieve high enough blood testosterone levels at the recommended dosage. The article says: The FDA has turned down Lipocine Inc.'s Tlando, an oral testosterone product candidate for testosterone replacement therapy in adult males...

A new study finds an increased risk of venous thromboembolism (VTE) in the six months after starting testosterone replacement therapy compared to the six months before the therapy was initiated. The abstract says: This case-crossover study analyzed data on 39 622 men from the IBM MarketScan...

Putting non-hypogonadal men on testosterone in order to reverse muscle wasting. The article says: Eighteen non‐hypogonadal healthy older men, 65–75 years, were assigned in a random double‐blinded fashion to receive, biweekly, either placebo (P, saline, n = 9) or T (Sustanon 250 mg, n = 9)...

A new blinded study found that metformin reduces muscle growth from resistance training. A cautionary note to those taking it for anti-aging purposes. The full text of the study is available at the link. Progressive resistance exercise training (PRT) is the most effective known intervention for...

I haven't seen this reported on the forum. Major pharmaceutical companies are reporting a shortage. There is no clear reason why: Cipla has testosterone cypionate injection on back order and the company cannot estimate a release date. Hikma has testosterone cypionate 200 mg/mL 1 mL vials on...

From The Lancet Journal of Diabetes and Endocrinology: Our meta-analysis showed that, compared with placebo or a comparator (eg, oestrogen, with or without progestogen), testosterone significantly increased sexual function, including satisfactory sexual event frequency, sexual desire pleasure...

High LDL cholesterol is a proven risk factor for heart disease. It can be controlled in most patients by weight loss, dietary change, and exercise if they are willing to commit to a significant change to their lifestyle. There is a minority of people who, for genetic reasons, cannot control...

A letter to the editor about the article. I can only conclude more doctors need to find out about Low T the hard way. As a GP I read your article about testosterone replacement therapy with interest. I was disappointed it did not mention the 2016 review that concluded that testosterone...

The Guardian did a very favorable article on testosterone therapy which surprised me: “Despite my medical training, I bought into the cultural narrative that with a busy lifestyle, these symptoms are nothing more than normal ageing,” he says. A GP wrongly concluded that Vossen’s symptoms were...

If you click on a link on Google's search results page, Google knows that you clicked on it. This helps Google improve its search results, but more importantly also lets it know what you are interested in so it can tell advertisers. If this bothers you use Duck Duck Go.

The article says the draxe.com was a big winner after the update, which surprises me, because the doctor is a chiropractor who I would consider an alternative health spokesperson.

I think this effect has been known in the bodybuilding community for some time, but it's good to have a study to back it up. The study was funded by the Department of Defence. "The research reported in this publication is supported by the Collaborative Research to Optimize Warfighter Nutrition...

A recent meta-analysis looked at the benefits and risks of testosterone therapy for postmenopausal women and concluded it was a safe and effective way to increase libido. The summary is available online, here is the conclusion : Testosterone is effective for postmenopausal women with low sexual...

Here's more information on the study from an editorial in MedScape: Renoux and colleagues' latest work provides no easy answers, despite a large cohort of 15,401 men, aged 45 years or older (mean 60.4 years), diagnosed with low testosterone without evidence of hypogonadotropic or testicular...

Presumably, these are all men under the British NHS. The standard for treatment is strict and those with low testosterone are likely to have a host of other health problems, including pre-existing heart disease.

A newly published study found an increased risk of stroke and myocardial infarction from testosterone replacement therapy. The risk was elevated for the first two years of treatment, suggesting that there is a subpopulation at risk, presumably those with existing heart disease. The journal...

A study duscussed at the Endo 2019 conference showed significant long term weight loss in men treated with testosterone therapy. While it's preferable to lose weight through diet and exercise, the long term success rate for thes changes are low. So having a pharmacological treatment which...

I used to have a problem with anxiety. I found out that there were dietary triggers (gluten and corn in my case) and dropping these foods from my diet improved anxiety a lot. There are effective non-drug ways to deal with anxiety. First, HIIT style exercise helps work off the energy that feeds...

This article argues that the risk of high hematocrit from Testosterone Therapy (TTh) is overstated: Clinical guidelines indicate that hematocrit should be monitored during testosterone replacement therapy (TTh), with action taken if a level of 0.54 is exceeded. We focused on literature...

A study evaluated the quality of online information about testosterone. Blogs and forums such as this one were excluded from the study. The complete text of the study is online. The conclusion was: "Information about TRT on the internet is not comprehensive, often failing to adequately describe...

There's a review of Royal Medical Center over on Reddit. The review is positive, but the client hasn't been with Royal for very long. There's some comparison with Defy in the comments, mostly about cost. Here's a excerpt, but if you have time read the whole review. "They are not shy to tell you...

Two studies recently in the news show the effectiveness of testosterone replacement therapy in the management of tupe 2 diabetes. The first was presented at the Endocrine Society Annual Meeting. An observational registry study of 462 men with obesity and hypogonadism. Among the cohort, 273 men...

I don't understand the mechanism at work here, but the design of the study seems sound. To reduce the risk of kidney stones, stay well hydrated and don't use calcium supplements. This news article cites the study: "We conducted a population-based matched cohort study utilizing data sourced from...

Another review article on TRT has been published and its abstract is available online. "Objective of the authors was to systematically review the relevant literature assessing the benefits and harms of TTh [testosterone therapy] in men with sexual dysfunction. Randomized and non-randomized...