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Before starting trt my e2 was 9 pg/ml so maybe normal for me is in the low range.

No symptoms, I'm getting big and ripped, I can get a hardon on demand, and I feel pfuking great!

Proviron inhibits the enzyme that converts test to e2 I think

Adding DHT into the mix will only make SHBG more saturated and unable to bind e2 I don't think albumin binds testosterone or other hormones not sure about steroid users crashing their e2. Never heard of any cases but I haven't looked

Well I did crunch the numbers and it looks like I have approx. 1000x more testosterone molecules compared to SHBG protein (micro-molar levels versus nano-molar levels) since 1 SHBG binds 1 molecule of testosterone, and since I have an excess amount of testosterone, one would assume all of my...

Here is the paper I read the other day stating shgb monomers bind a single hormone. I just cy and pasted the relevant paragraph rather than posting the whole paper, but feel free to look it up for yourself if youwant Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific...

Well, let me state it the correct way. If total e2 is unbound, free e2=total e2. Not the other way around lol.

and free e2, if it is completely unbound isn't a fraction of total---free is the total LOL

actually it is 2 binding sites per dimer...since they exist in homodimers. regardless, I bet my shbg is saturated... anyways that point about 1 binding site per shbg is irrelevant anyways... to summarize, because the complex exists as a dimer (meaning 2 shbg are bound together, which hold a...

I dont have access to the journal article at home, only at work so I'll find it tomorrow haha

anyways I'm looking into it. All I know is I get massive e2 symptoms with 2x ai per week

Not sure if this is true but I think the combination of having low shbg and high total test allows me to have more free e2 in circulation...maybe this is part of why my libido is super strong. As you know shbg can bind only 1 molecule of hormone--either testosterone, e2, dht, or some other type...

I have night time erections, morning erections, and my sex drive is insane...so I suspect it is a little more complicated than just estrogen levels driving libido. When I was on 2x AI a week I didn't have any sex drive, and I could barely get it up. I have additional test results but figured...

The doc who saw me when I first developed gyno said it would go away, said it was common and not to worry about it (grrr).. She did blood tests that reveled low total serum test (220ng/dl), but low normal free test. she said I was normal... Estrogen was not checked. Anyway, I lived with it...

I had gyno when I was a teen and know what my nipples felt like when I first developed it. Same feeling. In addition, I was holding a lot of water (bloat) I attribute to having non-optimal estrogen levels. The doctor agreed and bumped me up a notch on the AI. My erection quality and libido...

Hi all - I am new here. Just wanted to share my blood test results after being on TRT for about 1 year now. My protocol is 0.27 ml test cyp (54 mg) subQ with 0.25 ml HCG (250 iu) every 3 days. I also take arimidex @ 0.5 mg 3x a week spaced out. I originally used arimidex at 2x per week but...