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  1. M

    Supplementing T4 with thyroid Labs

    I have had over 10 years of experimenting with every form of thyroid replacement (sustained-release T3, T4 monotherapy, T3 monotherapy, commercial NDT, custom-compounded NDT, T3 + NDT, T4 + NDT) and I have found the most effective to be custom-compounded NDT which I have made with ascorbic acid...
  2. M

    Most people don’t need TRT

    Big topic. Lots of debate. The + and - of TRT will never end. If you haven't already, why not try a secretagogue that helps your body produce it naturally with none of the TRT-related side effects or negative feedback loop issues (i.e. Enclomiphene, hCG, Kisspeptin-10)? That's what I'm...
  3. M

    Kisspeptin Dosage

    In my first trial with KS-10, my total T levels increased 40% after a month on 100mcg/day (You can read about it on my previous post here) - but - I was also taking tesa/ipa/cjc which may have an influence on T levels as well. I am now awaiting the labs after upping the dose of KS-10 to 100mcg...
  4. M

    Beta-blocker responsible for significant ED, searching for BP meds that don’t cause ED.

    If you can't get brand nebivolol via insurance you can try getting it via the Abbvie Patient Assistance program for 0 out of pocket or getting it cheap as a generic since that is now available.
  5. M

    Beta-blocker responsible for significant ED, searching for BP meds that don’t cause ED.

    I would look into Bystolic (nebivolol). It is a 3rd generation beta blocker, is far superior to any of the previous generation BBs, is neutral or beneficial on lipids, glucose and insulin sensitivity, and is the only BB that produces endothelial nitric oxide. I combine it with Mycardis...
  6. M

    Semaglutide Forum: Game Changer for Weight Loss

    Beyond semaglutide and tirzepatide. Stay tuned for a TRIPLE AGONIST now in Phase 2 trials coming soon to a pharmacy near you: https://www.insider.com/new-weight-loss-and-diabetes-drug-retatrutide-awaits-further-testing-2022-12
  7. M

    Bubble gut – VAT, SAT, both - or something else

    Did your hernias come from improper form, straining during lifts and not strengthening core enough?
  8. M

    Anyone succeeding in increasing T with Kisspeptin while on TRT

    My levels increased 40% after a month on 100mcg of KS-10 from Peptide Sciences. I am now doubling the dose to see if I can increase it further. You can read about it on my previous post here.
  9. M

    Bubble gut – VAT, SAT, both - or something else

    Were they succesful? Was mesh used?
  10. M

    Bubble gut – VAT, SAT, both - or something else

    Did you have the hernias surgically repaired?
  11. M

    Bubble gut – VAT, SAT, both - or something else

    Did you have surgery to correct? Looks like DRA can be corrected sometimes with certain exercises but not always. May take too long and not reverse. Umbilical hernia can only be corrected with surgery. I think I should talk with a surgeon to get his take. According to Heath, his surgery went...
  12. M

    Bubble gut – VAT, SAT, both - or something else

    I had no idea Phil Heath had DRA + double hernia + intestinal strangulation! https://muscleinsider.com/news/phil-heath-undergoes-hernia-surgery...
  13. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    Any papers to show that? Everything I've seen is that it is a driver for diabetes, CVD and malignancies.
  14. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    So, 100mcg in a.m. and 100mcg in p.m. as an example. Any thoughts as to the risks of elevated IGF-1 levels from the GH secretagogues?
  15. M

    CCTA vs CAC scan to detect atherogenic plaque

    Has anyone done a CAC scan and CCTA and observed a wide difference in results? My recent CCTA (coronary computed tomography angiography; see below) showed "no evidence of coronary atherosclerotic plaques or coronary artery stenosis". This is in direct contrast to the CAC scan I had done in 2021...
  16. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    Big n-1 results update. With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - - Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES...
  17. M

    Latest Update on Metformin

    A recent metformin study casts doubts on longevity indications Thoughts?
  18. M

    Bubble gut – VAT, SAT, both - or something else

    Is this an alien baby about to burst out of me? You can see the protruding midline bulge when I lay on my back and tilt my neck up. You can also see an umbilical hernia. I really wonder whether specific PT core exercises will fix this over time - or if this will eventually require surgery. I...
  19. M

    Carpal tunnel symptoms and peptides

    I'm already taking Telmisartan and it still ddn't subside. Strange.
  20. M

    Carpal tunnel symptoms and peptides

    Anybody experience carpal tunnel syndrome symptoms (i.e. numbness in index finger, thumb and middle fingers) and body aches from GH peptides (tesamorelin, ipamorelin, etc.) especially when waking? I understand that CTS is a very common side effect with GH itself. What did you do to remedy it? I...
  21. M

    BPC-157/TB-500 Dosing

    I have done independent purity analysis of Peptide Sciences peptides including BPC-157 and all have come out at least 99% pure. I was formally skeptical about using any non-pharma-grade research peptides. Although I have not used nor tested other purveyors, Limitless Nootropics is one of the...
  22. M

    Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

    Which one did you try? From your DEXA scan, it sounds like it did its job.
  23. M

    Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

    Has anyone done a DEXA scan before and during use of any GLP-1 agonists (semaglutide, tizepatide) to assess body composition? In Peter Attia's recent blog, he eludes to the fact the GLP-1 agonists can cause loss of lean mass (in addition to fat loss), of particular concern in non-obese persons...
  24. M

    Bubble gut – VAT, SAT, both - or something else

    Thanks. SIBO has been a likely issue. Already on Metformin (as a geroprotective and prediabetes prevention) and have been taking betaine HCL and pancreatin for years. I have done extensice gut biome testing. I tend toward IR, hence the metformin and many other supplements + LC diet. Working on...
  25. M

    Steroid Belly: Anabolic Steroids Increase Visceral and Decrease Subcutaneous Fat in Bodybuilders

    Tesamorelin (Egrifta) also reduces VAT without the AAS side effects.
  26. M

    Bubble gut – VAT, SAT, both - or something else

    I'm assuming to check for herniated discs, disc degeneration, etc.? I've had painful episodes of lumbar issues on either side for the last several years from unintentional hyper-extending of the back during heavy lifts.
  27. M

    Bubble gut – VAT, SAT, both - or something else

    So I tried the exercise and can only fit one finger. But there is a ridge/bulge when I do which is described here. So I still don't know for sure. Can the abdominal region still stretch and distend without separation? Will need to get to a doc that can properly diagnose it.
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