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I'm a 46 yo male, 150lb, 5' 6", been on TRT on/off for almost 3 years. After trying 6 months off of TRT (not fun), I restarted at a lower dose of 16mg every other day subq of cypionate/propionate blend (160/40/mg/ml). Previously I was dosing 20mg every other day, but had elevated hematocrit of...

Agreed. What about starting low and going slow so your body can adapt? I experienced negative side effects when I started that went away over time. I also second the recommendation to work with Defy.

I'm sorry to hear that you're having a rough time. I'm not a doctor, but throwing a few things out there for consideration: 1) Have you considered working with a good functional medicine doctor? I've found that the diagnostics are much more thorough/evolved, and that they're generally much...

I have used a Dexcom G6 extensively. It requires a prescription and costs more out of pocket, but I strongly prefer it because it can be calibrated. Calibration is important for accuracy when you are a non diabetic and swings in blood sugar are smaller. I believe that CGM’s will be the standard...

Fair point, Nelson. My goals would include: 1. Subjective well being: energy, physical output, return of libido 2. Labs: Free T mid-reference range or above, with hematocrit within rr, estrogen within rr, no rise in BP 3. Doing what I can to maintain endogenoous feedback loops Thank you!

Was hoping to get some input... As a reminder I was having issues on TRT (decreased libido, high estrogen, increased bp, high hematocrit etc). Because of this I stopped injectable testosterone (after close to 2 years) on April 2, 2022 and began this restart protocol: * 5 weeks of HCG 1500-2000...

I take 150 mg of pregnenolone daily. I like the micronized version by Allergy Research Group. Taking it has been a game changer for me, as my levels were non detectable after extensive toxic mold exposure. One thing I’ve found re testing…I usually take my dose in the morning, but based on the...

Yup. This has been my experience as well. Clomiphene tanked my IGF-1. Curious if this correlates to lowered growth hormone production...

Thank you! I ended up working with my doc and getting scripts for both. He's $165 for 15 minutes but worth it given his knowledge and willingness to write scripts.

Can anyone direct me to a site that can provide a script for Natesto and a script for enclomiphene? I'm trying to avoid the high consult costs of my current doc, but will go that route if needed,,,,thank you.

Been listening, great share! Shallenberger is the father of ozone....which I'm a HUGE fan of....done it alot and it's helped me tremendously.

re: Jatenzo...so sounds like there isn't the negative impact to organs that used to be attributed to oral administration?

Great data!

-Noted re enclomiphene vs clomiphene, will do. -Any suggestions on a restart protocol? I've now stopped TRT. I wasn't sure what the latest thinking is on this and am considering: HCG 400iu daily X 14 days, followed by enclomiphene 25mg daily X 28 days -Post restart, and after running labs...

Great callout regarding DHEA, thank you! And good to know re Jatenzo.

For my specific situation pregnenolone had the biggest positive impact...my natural levels were close to undetectable due to my history with mold. Hydrocortisone helped for a period of time when I needed an adrenal reboot...I've found that a saliva cortisol test is the best way to check. I...

@Mark Saur I have in the past...forgot to run it this time. Important one...thanks! Been on 30mg armour and I'm considering adding some T3 to see if that may have an impact.

@Guided_by_Voices I appreciate you weighing in! You are spot on re attempting to get to the root of fatigue issues with a good functional medicine doctor. I've worked with some of the best functional medicine docs around (spending more than the GDP of a small African country in the process)...

@Cataceous thanks so much for such a detailed and informative response. Greatly appreciated! Great suggestion re Natesto. Wondering if Natesto and hCG or Natesto and clomid might be the way to go? I'm leaning towards one of these combos as a next step... If I decide to stay on TRT, I will add...

Thanks for the response, @Willyt, I appreciate it! I've stopped TRT for the moment, cycling in some hCG and clomid to kickstart the system, and currently assessing what move to make next...

5' 6"

Hi there! I just posted for the first time and went back to attempt to edit the post, make a few corrections, and update some data. Just confirming, does this functionality not exist? Thanks so much for everything! Greatly appreciate this forum and site.

I’m a 45 yo male, 150 lbs. Prior to starting any testosterone therapy my labs in January 2018 were in range (Total T 601 280-1100ng/dl, Free T 10.43 1.9-27ng/dl), but I wanted to see if increasing testosterone levels would help to improve fatigue. I always had a high sex drive, with decent...