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Yes it can, it did for me. I had a very low DHEA-S level on TRT and supplementing DHEA only made me feel worse. After coming off TRT my level went back to normal.

Does any of the supplements you're taking contain saw palmetto? That has the potential to kill libido.

Interesting article but they don't specify what they use as the normal range for TSH in this summary of the paper. Maybe the full text would have that information. Thyroid Hormones May Increase Risk of Cognitive Disorders in Older Adults Patients age 65 and older who receive thyroid hormone...

Supplementing DHEA, even at doses as low as 12.5mg per day absolutely ruins my sleep. I've learned just to accept low DHEA-S on my labs.

It really depends on your insurance company, some will require you to get off of testosterone and then get 2 morning readings 4 weeks apart below 200. You could try calling your insurance company and asking for their medical policy document on TRT or searching their website.

You're paying Defy for their expertise, do what they say and then stay off the forums unless you have issues down the road.

I'm sure pharmacists must have any easy way to fill these syringes and it was super easy for me to dispense the prescribed amount.

When I was with Dr. Shippen the compounding pharmacy he used would put the cream into standard 1ml oral-topical syringes to allow for precise dosing.

I'm off TRT entirely now, but I had done up to 4 clicks per day from a Topi-click of 200mg/ml cream and had lower HCT than even 60mg/wk test.cyp. The cream will spike your DHT, and likely testosterone, to super-physiological levels for several hours after application.

The only way I was ever able to get my HCT down was by switching to T cream.

Lyme disease, ME/CFS, Long Covid, any number of conditions could be causing your issues. It seems like you've ruled out hormonal issues so you should start trying to rule out some other conditions.

Found out my insurance covers it at 50% coinsurance, so it would cost me $220/month. That's out of reach for me.

Thyroid levels aren't great, at least according to the internet. I'm on thyroid meds but can't increase my dose much higher without exacerbating my insomnia. I know you've found success with Jatenzo, which is something I haven't tried and I'm not sure if I could find a doc willing to prescribe...

I was on TRT for about 10 years, spent a lot of time on the forums thinking that if I just kept at it and found the right doctor and the right protocol I would get some of the subjective benefits people talk about. 3 months ago I quit cold turkey, a partial list of my current labs are as...

I was taking NP Thyroid, I forget how many grains. Now I take 50mcg generic synthroid and 15mcg generic cytomel.

That's the body's normal inflammatory response to being infected you're feeling, you don't need more Paxlovid.

I switched to synthetic T4/T3 years ago and haven't looked back. Also gives me the ability to adjust the ratio of T4 to T3.

How many hours after your last application of cream was the lab draw?

Oral minoxidil in alopecia

Once daily application of low dose testosterone cream (3mg) has also been shown not to suppress LH and FSH. The study claims an improvement in aging male symptom (AMS) scores even at such a low dose. The efficacy and safety of short-acting testosterone ointment (Glowmin) for late-onset...

I didn't feel anything starting SSRI's, several different types at different times. Nor did I feel any different after reaching steady state and being on them for months. Which is to say I felt like crap before, during, and after taking them.

Wow, that's quite the list. How many doctors did you have to see to get that many meds prescribed? I took a boatload of AD's before finding out I had low T, hypothyroidism and other health issues, but I only got to try about half the drugs on your list. I also found that none of the ones I tried...

My only issue was the suggestion that there was no clinical data collected in humans, and that the FDA was moving ahead only with data collected it mice. The human data, as limited as it is, has been publicly available since June. If you are interested in a thoughtful interview with a member of...

The human trial data submitted by Pfizer/Biontech is summarized in this presentation submitted to the FDA. The data in mice is also included. This data has not gone through peer review. https://www.fda.gov/media/159496/download

Well, he's clearly misinformed on the booster vaccine approval process.

Not a good idea to get your info from a place like USAToday. Try this.

It is not a given that this will happen for most men who go on TRT. In fact, I have a few friends IRL who have tried TRT, as well as myself, and once getting past the honeymoon phase none of us have had much of an improvement in these areas. A couple even quit TRT entirely because they said it...

Yes, we tried some options to resolve the issues. I'm currently still on low dose TRT.

Yup, I was one of them.

Draw about 5 to 10% less with each injection. You will get a slightly lower dose, but you won't have to worry about running out.

You must have bought it from a peptide site. I've been buying from Empower Pharmacy and it doesn't come with any of those warnings.