Blood work lab opinions

Would love to see others analysis of my blood work from the the other day. At the time this was taken I was doing 200mg test cyp weekly and these labs are from bottom end of 7day cycle with the next day being my shot day. I have since in the last 2 weeks switched to twice a week 100mg each time. I'm currently 6'4 290lbs and working to recomp down to 225-250 range.

Well you have iron deficiency without anemia indicated by the low MCH and MCHC. RDW typically is elevated when you're iron deficient, you're almost there.

Your hemoglobin is bottomed out at the lower end with very high FT, TRT increases hemoglobin, decreases ferritin/iron stores.

TRT won't increase hemoglobin if your iron stores are low. Some men will never become anemic on TRT because T therapy drives up the hemoglobin more strongly than natural T production. These men will find their ferritin in the low teens with low MCV, MCH, MCHC and high RDW.

If you have iron deficiency, you can expect to see low HDL, which you do.

You'll may become anemic very soon.

SLADE said:

Would love to see others analysis of my blood work from the the other day. At the time this was taken I was doing 200mg test cyp weekly and these labs are from bottom end of 7day cycle with the next day being my shot day. I have since in the last 2 weeks switched to twice a week 100mg each time. I'm currently 6'4 290lbs and working to recomp down to 225-250 range.

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You are clearly overmedicated here.

Most men on TTh are injecting 100-200 mg T/week whether once weekly or split into more frequent injections as in twice-weekly (every 3.5 days), M/W/F, EOD or daily.

Even then most men can easily hit a healthy let alone high trough FT injecting 100-150 mg T/week especially when split into more frequent injections.

As I have stated numerous times on the forum over the years yes there are some outliers who may need the high-end dose 200 mg T/week but it is far from common as in RARE!

Such dose would be OVERKILL for the MAJORITY!

Common starting dose is 100 mg T/week or better yet 50 mg every 3.5 days.

Starting low and going slow on a T-only protocol would be the most sensible move as we want to see how your body reacts to testosterone and where said protocol (dose of T/injection frequency) has your trough TT and more importantly FT, estradiol let alone critical blood markers RBCs, hemoglobin and hematocrit.

Although your trough TT 776 ng/dL may not seem very high with a low SHBG 16.2 nmol./L it is a given that your trough FT would be high.

Shitkicker here is seeing as you tested at the true trough (7 days) post-injection than your TT and more importantly FT let alone estradiol will be absurdly high!

You had your FT tested using the known to be inaccurate direct immunoassay.

No one should be using/relying upon such let alone any doctor in the know would test your FT using the gold standard Equilibrium Dialysis especially in cases of altered SHBG or at the very least if one did not have access to such (highly doubtful) if you reside in the US than at they would use/rely upon the calculated linear law-of-mass action Vermeulen (cFTV).

In order to know where it truly sits you would need to have it tested using what would be considered the most accurate assay the gold standard Equilibrium Dialysis.

You can pay out of pocket and use Nelson's DiscountedLabs.com to test your TT and more importantly FT using the most accurate assays (LC-MS/MS-ED).

$48.83

Have you been donating blood?

Your VitD is on the bottom end.

B12 is too high.

Your triglycerides are high.

HDL is low!

Bad move splitting your whopping weekly dose 200 mg T ---> 100 mg every 3.5 days!

All you are going to do here is clip your peak/tough so although you will bring down your absurdly high peak TT and more importantly FT you will be pushing up your already high trough FT further!

If anything you would need to lower your weekly dose!

You are most likely carrying a fare amount of adipose so you are going to be a heavy aromatizer and the last thing you want here is to be running a high trough FT!

Curious madman where you get the comments of absurdly high? In most optimized communities TT of 30-50 is recommended. We all now the lab ranges are a complete joke. Based solely on my on knowledge of watching them over the last 13 yrs of being on Trt and through this site. Yes i give blood regularly every 8-10 weeks and have since i was 18 and had just donated a week before this test. Im truly interested in what you think i should be looking for numbers wise and where you get that info from. I increased my vitamin d 5,000iu daily after this also. Yes im big guy but according to dexa i have 227 lbs lean mass and 22.4% body fat. I look forward to more info you have and research to follow up on.

SLADE said:

Curious madman where you get the comments of absurdly high? In most optimized communities TT of 30-50 is recommended. We all now the lab ranges are a complete joke. Based solely on my on knowledge of watching them over the last 13 yrs of being on Trt and through this site. Yes i give blood regularly every 8-10 weeks and have since i was 18 and had just donated a week before this test. Im truly interested in what you think i should be looking for numbers wise and where you get that info from. I increased my vitamin d 5,000iu daily after this also. Yes im big guy but according to dexa i have 227 lbs lean mass and 22.4% body fat. I look forward to more info you have and research to follow up on.

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I stated that your trough FT (7 days post-injection) is going to be high with a robust trough TT 776 ng/dL and low SHBG 16.2 nmol/L which means that your peak TT and more importantly FT will be absurdly high (almost double) 8-12 hrs post-injection during the first 2-3 days every week!

If we calculated your trough FT using the linear law-of-mass action cFTV you would be in the low 20 ng/dL which is high!

A trough FT 30-30+ ng/dL is absurdly high compared to where a healthy young male would sit 12 ng/dL (paper posted thread below post #23) and this is tested using the most accurate assay, gold standard direct state of the art ED LC-MS/MS assay in healthy men, blood drawn in the early AM!

Again outliers are the ones that would be hitting the 90-95 th percentile and this would be far and few.


We present 95% mFT age-stratified reference ranges



Even if you took a natty outlier hitting a high FT 20-25ng/dL this is a short-lived daily peak we are talking about here not a trough let alone trough 24 hrs (daily), 48 hrs (EOD), 72 hrs (M/W/F), 84 hrs (every 3.5 days) let alone 168 hrs (7 days) post-injection!

You get the point here!

Top it off that there is no such thing as a natty healthy young male running around with a peak let alone trough TT 1000+ng/dL and more importantly absurdly high FT with low/lowish SHBG, such does not exist!

Most healthy young males are hitting a TT 500-600 ng/dL (peak), even going back to the 70s when testing was first available you would be looking at 600-800 ng/dL.

Take those TT 500-800 ng/dL (daily short-lived peak) and thrown in for shits sake a normal SHBG and calculate their FT using the go to linear law-of-mass action cFTV and none of these men would be hitting a peak FT of 20 ng/dL.

Top it off that cFTV tends to overestimated slightly compared against a standardized direct state of the art ED assay so FT would be slightly lower than the cFTV value given!

There is a reason we have a natural 24 hr circadian rhythm with T levels peaking in the early AM.

T was never meant to be elevated let alone amped up 24/7!

Bottomline here is if one feels great overall, minus any sides and blood markers are healthy than I see no issue running a high-end/high trough within reason.

You are clearly trying to manage elevated hematocrit if you are donating every 8-10 weeks as your RBCs and hematocrit are still sitting close to the top-end on your most recent labs and judging by your other CBC results you most likely crashed your iron/ferritin due to the frequent donations which can open up another can of worms.

Those knumbskulls pushing this so called magical optimal trough FT 30-50 ng/dL is pure nonsense.

Even than big difference between one hitting an absurdly high trough FT 30-50 ng/dL injecting daily vs twice-weekly vs once weekly!

A natty outlier hitting a top-end FT 20-25 ng/dL is high and again this is a short-lived daily peak we are talking about here!

You would be hitting a cFTV trough in the low 20 ng/dL and this is 7 f**king days post-injection!

So yes your trough FT is high and your peak FT will be absurdly high plain and simple!





Look over post #19/21/23!

Pay attention to post #23!