Do I Really Need TRT? Numbers Seem OK.

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I can supply any other numbers that may be needed, but for the sake of keeping it short here are my Testosterone related results below.

I inquired about TRT with the usual suspects of Low T, but now that I see these results I'm starting to think maybe I shouldn't be messing with my natural levels (T is over 800ng/dl, Free T is a bit low but still normal and then my SHBG is higher, but I do eat low carb and drink way too much coffee - so I could try adjusting that.

but overall, I was still given the OK for 100mg of test a week but now after seeing my levels I'm a bit hesitant on messing with them for 100mg of Test which in theory would only really bring me back to to normal, which I'm at anyway? Aren't I?

results below.

Reproductive and Gonadal

 

Reading

Reference Range

 

Estradiol

 

49

<162

pmol/L

DHEA Sulphate

 

9.3

<15.0

umol/L

Testosterone

A

29.3

8.4-28.8

nmol/L

Testosterone Free Calculated

 

389

115-577

pmol/L

Method of Vermeulen

   

Testosterone Bioavailable Calculated

 

9.1

2.7-13.5

nmol/L

Method of Vermeulen Interpret BAT and cFT results with
caution in presence of significant
hypoalbuminemia.

   

Sex Hormone Binding Globulin

A

72.1

10.0-70.0

nmol/L

    
 
Defy Medical TRT clinic doctor
I can supply any other numbers that may be needed, but for the sake of keeping it short here are my Testosterone related results below.

I inquired about TRT with the usual suspects of Low T, but now that I see these results I'm starting to think maybe I shouldn't be messing with my natural levels (T is over 800ng/dl, Free T is a bit low but still normal and then my SHBG is higher, but I do eat low carb and drink way too much coffee - so I could try adjusting that.

but overall, I was still given the OK for 100mg of test a week but now after seeing my levels I'm a bit hesitant on messing with them for 100mg of Test which in theory would only really bring me back to to normal, which I'm at anyway? Aren't I?

results below.

Reproductive and Gonadal

 

Reading

Reference Range

 

Estradiol

 

49

<162

pmol/L

DHEA Sulphate

 

9.3

<15.0

umol/L

Testosterone

A

29.3

8.4-28.8

nmol/L

Testosterone Free Calculated

 

389

115-577

pmol/L

 

Method of Vermeulen

   

Testosterone Bioavailable Calculated

 

9.1

2.7-13.5

nmol/L

 

Method of Vermeulen Interpret BAT and cFT results with
caution in presence of significant
hypoalbuminemia.

   

Sex Hormone Binding Globulin

A

72.1

10.0-70.0

nmol/L

     
What issues are you trying to address? Self-managing your hormones if you are in a good place to start with is generally a bad idea.
 
You have an estrogen deficiency, normal estrogen is 80> pmol/L for adult men. These estrogen values are fine for someone that hasn’t gone through puberty. The free testosterone values may not be normal for you.

The only way to tell is genetic testing Gene CAG repeats numbers that isn’t yet available to the general public. Total testosterone doesn’t define testosterone deficiency, the free testosterone does.

The total testosterone will be higher in men with higher SHBG. You basically have the same free testosterone levels as someone with a lower total testosterone and mid to lower end SHBG values.

Diagnosing low testosterone is not always easy or is there a clear known cutoff for each individual. This is why some providers offer a 6 month trial of TRT to see if it resolves symptoms.

If you don’t have any symptoms, you shouldn’t mess with your hormones.
 
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The only issue that I see is your high shbg. It may not be that big a issue right now, but eventually it may rise and become one.
 
Your E2 is in range as well [10 to 40 pg/ml]
A 13 estrogen value is a deficiency for most adult men. Too boot his SHBG is high binding up more of that estrogen. I had recently came on Cialis due to insane hot flashes, estrogen was in the low teens.

I recall members reporting osteoporosis with estrogen at 16.

These normal ranges are poorly defined and have nothing to due with quality of life or a healthy population.

If the OP has no symptoms he is an outlier.
 
Last edited:
What issues are you trying to address? Self-managing your hormones if you are in a good place to start with is generally a bad idea.
Lower than usual libido, some drive and motivation issues.


About 10 years ago I did a lot of anabolic steroids (Everything + Tren - nothing since) and came off pretty abruptly so I always had a hint my levels would be messed up.

Eventually I got tested by a 3rd party TRT company and they approved me for 100mg a week + HCG and Arimidex.

After seeing my numbers im hesitant to go with the 100mg since I'm not sure messing with my natural levels would be worth that?

I'm still waiting to receive my meds from the company but while I wait I've been wondering about all of this.

What could I do about the estrogen deficiency? what would cause that?
 
Lower than usual libido, some drive and motivation issues.


About 10 years ago I did a lot of anabolic steroids (Everything + Tren - nothing since) and came off pretty abruptly so I always had a hint my levels would be messed up.

Eventually I got tested by a 3rd party TRT company and they approved me for 100mg a week + HCG and Arimidex.

After seeing my numbers im hesitant to go with the 100mg since I'm not sure messing with my natural levels would be worth that?

I'm still waiting to receive my meds from the company but while I wait I've been wondering about all of this.

What could I do about the estrogen deficiency? what would cause that?
I've always had low estrogen both before TRT and with trt. It's never been an issue with me. Strong libido, good workouts. Nothing to complain about. As long as you eat properly, work out, you should have no issues with osteoporosis.

Testosterone, Serum 1254 ng/dL range 264-916
Estradiol, Sensitive 15.1.0 pg/mL range 8.0-35.0
I've never used an AI.
 



 
Lmao it's a no-brainer! with such #s i would just forget about it and try to live as healthy as possible ticking all the other boxes. Easy money for you right there. I have to take 100mg/week to get me to 29 test. You good with with such solid #s. Probably could play with SHBG and E2 to see if any manipulation makes a difference and just enjoy life without syringes and exogenous hormones, at least till later, a lot later it seems :)
 
Lower than usual libido, some drive and motivation issues.
Some men are in what's called the gray area, not deficient but an insufficiency and may progress to a deficiency. It's a spectrum, increasing androgens is like a raising a dimmer switch, the higher the levels, the brighter the light, the more androgenic activity and benefits.

At the end of the day quality of life is all that matters. Yeah, so wait 10-15 years until things get worse, then you can think about TRT and get your motivation and libido back to youthful levels and feel young again because that makes sense doesn't it.

Everyone thinks their going to live to be old age and retire, now is your time to live your life to the fullest, not later.

How old are you?
 
Last edited:
the higher the levels, the brighter the light


cen13840-fig-0001-m.png


Hmmm...


https://academic.oup.com/view-large/figure/59955215/eg0484704001.jpeg
 
Last edited:
Lower than usual libido, some drive and motivation issues.


About 10 years ago I did a lot of anabolic steroids (Everything + Tren - nothing since) and came off pretty abruptly so I always had a hint my levels would be messed up.

Eventually I got tested by a 3rd party TRT company and they approved me for 100mg a week + HCG and Arimidex.

After seeing my numbers im hesitant to go with the 100mg since I'm not sure messing with my natural levels would be worth that?

I'm still waiting to receive my meds from the company but while I wait I've been wondering about all of this.

What could I do about the estrogen deficiency? what would cause that?
I have t low E2 also so I am trying to raise it myself. Some things that can lower estrogen are common supplements like zinc, so I would review what you're taking and see if anything blocks the aromatase enzyme. While it's possible your issues are driven by T, going with TRT can cause other issues (erection issues for some) so I would start by reviewing everything else about your health first, and if you try anything hormonal, start with clomid or enclomiphene first, which are usually easy to discontinue. Your symptoms could be caused by a long list of things like lack of activity, poor sleep, poor nutrition (e.g. lack of omega 3 fats) , chronic infection or mold exposure, under-eating, overtraining, and other things as well, so like others said, I would look for other root-cause issues first.
 
Beyond Testosterone Book by Nelson Vergel
Once you start down the path of TRT, you are altering your natural balance. That is a good thing for those who need it, and a very unwise move for those that don't. Your labs look great, don't start tinkering with your hormones as it will not likely lead to a positive place.

Loss of libido and motivation can be caused by a multitude of factors. Also, all of those factors may be interconnected. ALWAYS try the natural approach first, lifestyle changes, dietary changes, emotional and psychological changes... take inventory of your current state and note any adverse factors. Make changes to any negatives noted.

Age is also a factor that needs to be addressed. Any advice given to anyone needs to have the age equation applied.

From my personal experience, most of the ailments reported by people are from toxic lifestyles and unreasonable expectations. Again... that pesky age factor. Things do change as we age.

My personal story regarding TRT is a good example of a really dumb move. In my 40's (yes, I am an old guy) I started looking into hormonal enhancement. My labs at the time were great, really great as a matter of fact as I have been a very solid health enthusiast and a lifelong gym rat with good genetics. But... I read a few books that were popular and "hot" at the time and thought I needed to be proactive. I started on TRT along with HCG and an AI which was the protocol of the day. All of this was in an effort to increase and maximize my hormonal profile. I had no symptoms of "low T" (God, I hate that phrase). I was going to make myself supernatural. Well... 20 plus years later, I am still on TRT and have dialed in a fairly decent protocol. BUT, and this is a VERY BIG BUT (I like big butts, I cannot lie) I could have waited another 10-15 years to start TRT, or perhaps not ever start to begin with. I went through all of the missteps that every other TRT user has complained about. Did I learn a few things? Yes. The first and foremost thing is that "If it aint broke, don't fix it".

Neurotransmitter imbalance is the likely cause of most of the common complaints you see on these forums. Lifestyles, environmental factors, stress and other things can get them off balance. The VERY good thing about this is that with some changes, they can be corrected. Forming new and positive neuropathways is a very solid way to regain balance in your life. Remove any toxic factors and start making new positive changes. The human body is a miraculous thing and has natural ways of repairing itself. This includes your brain and emotional health.


An old Cherokee is teaching his grandson about life. “A fight is going on inside me,” he said to the boy.

“It is a terrible fight, and it is between two wolves. One is evil – he is anger, envy, sorrow, regret, greed, arrogance, self-pity, guilt, resentment, inferiority, lies, false pride, superiority, and ego.” He continued, “The other is good – he is joy, peace, love, hope, serenity, humility, kindness, benevolence, empathy, generosity, truth, compassion, and faith. The same fight is going on inside you – and inside every other person, too.”

The grandson thought about it for a minute and then asked his grandfather, “Which wolf will win?”

The old Cherokee simply replied, “The one you feed.”
 
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