High Iron - Low Ferritin

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Perfect, that would be awesome, thanks
Here it is:
 
Agree. 23andme checks only for 2 variants of HH, AncestryDNA for 5+ I believe when you run there raw DNA data through checkiron.com algo. Got the sample sent myself and waiting for DNA results which should be done in 6 weeks time. NHS checked me for type 1 HH only which I'm negative, so looking to see what other mutations I have. I think absolutely more people should pay attention to it, esp the Carnivore crowd, as if you are loading Iron and smashing Beef on the daily basis without anything else to inhibit Iron absorbtion and without even knowing you have issues- it won't end well on the longer-term perspective.
As far as I know, the C282Y and H63D are the only problematic variants in terms of hemochromatosis and a conundrum in balancing with TRT. @FDV70 could shed more light on that probably.
 
As far as I know, the C282Y and H63D are the only problematic variants in terms of hemochromatosis and a conundrum in balancing with TRT. @FDV70 could shed more light on that probably.
Like I said, there are more types and even some carriers with only one copy might load Iron, so it def pays to explore all the HH types running raw AncestryDNA data through checkiron.com as its the largest up-to-date HH database available and free. Had a chat with the main guy behind it- great, smart guy, always there to help and share his views if needed. Just my 2 cents.
 
I’m at a loss as to why your doctor wants you to donate blood! I suggest you find another doctor because this one is f***ing clueless!

Your hematocrit levels are typically seen in people living in high altitude populations like Boulder, Colorado, no one‘s telling them to go donate blood.
thats not true.. they def do lol. your at grater risk of CAV living at altitude for this reason, the people who live in mountains and grow old are usually 4-5 feet tall..
 
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On my last blood test (June 21st) my Iron is too high and my Ferritin is at the bottom of the range. I've read Ferritin needs to be at least over 70 ng/mL but around 100 ng/mL is optimal. My last blood donation was April 08, I stopped donating because on May 07 my Iron and Ferritin was really low. My liver enzymes checked good and no infections. I eat a lot of red meat so should be getting Heme Iron. Any suggestions why my Ferritin is not increasing like my Iron did? My doc just emailed and said to donate blood again, I've not been able to have a conversation with him yet. Some test results below.

April 08, 2024 - Last Blood Donation

May 07, 2024 - Test Results

Ferritin - 15 ng/mL (L) (22-322)
Iron - 36 ug/dL (L) (65-175)
Transferrin - 430 mg/dL (H) (215-365)
TIBC - 538 ug/dL (H) (218-385)
%SAT - 7% (L) (20-50)

June 21, 2024 - Test Results
Ferritin 37 ng/mL (30-400)
Iron - 206 ug/dL (H) (38-169)
TIBC - 447 (250-450 ug/dL)
UIBC - 241 (111-343 ug/dL)
Iron Saturation (TSat) 46 (15-55%)
RBC - 6.53 (H) (4.14-5.80)
Hemoglobin - 16.8 (13.0-17.7 g/dL)
Hematocrit - 51.6 (H) (37.5-51.0 %)
MCHC - 32.6 (31.5-35.7 g/dL)
RDW - 17.5 (H) (11.6 - 15.4%)
Platelets - 219 (150 -450)
 
its normal for Ferritin to drop whilst being on TRT. The increase in red blood cells signals your body that it doesn't need to store iron
 
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