Recent content by wannabefan

I’m just going to add my experience on cream over last 2+ years. Cream is unpredictable and cannot be tightly managed. I’ve seen T and Free T and DHT move from 400/90/60 up to 900/200/200, only to drop when taking labs more than 12 hrs after last application. More recently, I saw labs of...

Would think this depends on route of administration and dosage. Cream format for me no side effects after 2 years other than weight gain which I suppose is from cell volume expansion and fluid retention along with a few lbs of muscle added. The other “side effect” with that is clothing.

Same test cream product used, 1 click per day at scrotal area produced 1200 T, 263 Free T, 40 E2. After 6M alternating scrotal and upper inner bi/tricep area (same total dose), produced just 266 Total T, Free T of 56, and E2 of 22. Second labs tested 28H after prior dose. First labs tested 4H...

My Atrevis top click bottle is: “20% Testosterone in Atrevis Hydrogel / 22.5ml” As noted, 1 pump click applied to scrotum resulted in TT 1200, FT 260, and based on historical use at 2 clicks a day, DHT is over 280, but no acne or hair issues whatsoever, just a gain of 6-8lbs of muscle and fluid...

1 pump, 50 mg on scrotum, total T measured 4-5 hours post dose was TT 1200, FT 220. Plan to alternate to inner bicep QOD.

I seem to convert T to DHT. At mild-moderate doses of 100-150mg T cream/day, my DHT levels run around 200. T levels range from 650-800, E2 30, SHBG 30. I have no clinical signs or symptoms to the negative whatsoever. What is the short and long term impact of running such “high” DHT levels? HCt...

It sounds like you may actually need a metabolic workup and a complete insulin resistance challenge test, some monitoring, etc. before you tackle TRT.

Intermittent fasting and a CGM would help.

It’s unclear if at the time of your serum labs if you had washed out prior TRT. You have LH so I assume you were either “coming down” from TRT or had fully washed out prior use. DHEA is upstream Testosterone, and feeds T. You have shown the metabolite “S” of DHEA. I would want a fuller picture...

You appear to be supplementing with DHEA. You might stop. You might get a Pregnenolone lab. You might get a urine metabolite (DUTCH) test, and see if you are a responder/converter. You might get a DHT lab.

FWIW after 6 weeks of 200mg QD cream, HCt went from 46 to 50, and back down after stopping. It’s not the cypionate.

Not knowing your baseline levels isn't ideal, but it would appear something is off with lab values and I would have redrawn. A Hct of only 48 would indicate T isn't being pumped as much as they go hand in hand. I assume your LH is 0.

Wow you are a hyperresponder to DHT conversion pathway. What are your E2 levels, baseline and post-cream application as measured? What has happened to your SHBG levels? Assume your LH went to 0?

My SHBG dropped in half after 6 weeks of cream, then measured at 4 weeks off. All other labs mostly came back, except DHT, so I will test again in 6 weeks or so.

I felt good on T cream, 6 weeks (didn't feel bad really prior, just wanted to optimize). I am off now, 4 weeks+. My levels returned for most part, although DHT and SHBG are below baseline. T back to within 90% and LH back 100% (happy for that). I will consider going back on again. PSA stable...