Recent content by Guided_by_Voices

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    The Coronary Calcium Paradox: When Higher Scores May Mean Safer Arteries

    The problem with this reasoning AFAIK is that calcified arteries are not good either since the artery is supposed to be flexible and calcification prevents much of the flexibility. What is supposed to happen to the soft plaque is that the body grows a new layer of endothelium over it and absorbs...
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    Frustrated with bloodwork. Daily injections, lowered dose, no AI.

    I have found the same thing. Hydration is critical to the point where I am drinking water it the waiting room for my blood draw. Be thankful you are optimized in what matters. Feeling great with high E2 is IMO better that feeling great with low E2, which is a problem for some of us. I wouldn't...
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    I just started Wegovy yesterday.. Nauseous already :)

    You make a good point here that I think deserves emphasis. The bulking and cutting rollercoaster that has become almost standard in the lifting world is the very opposite of consistency and I think leads to a lot of bad outcomes. In particular I notice a lot of people who over a period of a few...
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    Gene's Nitric Oxide Stack

    If your doctor won't provide one, many of have ordered from alldaychemist with good results. Also note that there are now Nitric Oxide lozenges available which have only been out in the last year or two.
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    A bit frustrated right now after my first appointment...

    I echo Nelson's comment. Hormone/health optimization is not about a few numbers on paper but about wholistic life approach. Defy are well-regarded specialists and have lots of option available as well as specialized expertise. Reading between the lines, it sounds like the doc you went to is...
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    Minimum testosterone to get a growth advantage

    - I am not sure of all of Primo's impacts, but it seems to me that oxandrolone is the lowest risk anabolic option for what you are after since lowering your T dose should lower your E2. -I was referring to GH secretagogues, not GH, although GH is fine to try to. IME it is lower risk than...
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    Minimum testosterone to get a growth advantage

    I agree with Nelson that oxandrolone and nandrolone (preferably NPP to start with, IMO) are better add-on options. Primo seems to blunt sex drive in some people, possibly due to its interference with E2 and IMO is overrated unless that doesn't happen for you. Oxandrolone at a low dose like 10-12...
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    Ancedotes of feeling better when taking time off injections.. Science behind this?

    Another avenue to explore is the degree to which Testosterone is a "signaling" molecule which trigger effects that last long after the actual T (and possibly metabolites like E) are out of the system. I don't know the biochem in detail, but we have had people here who for example were injecting...
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    Skipped 3 pins and felt great

    There are many points of view on this topic, but my two cents is to try going without pinning for as long as you can and then when symptoms reappear, inject a low-moderate dose and repeat the process. T is (among other things) a signaling molecule and some people may do better at much longer...
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    Tinnitus

    I find potassium supplementation to be step one for BP. Contrary to popular belief, low salt can also cause high BP in some people. Cold temperatures can also cause a seasonal rise. It seems like trying other meds like telmisartan or possibly an ACEi is worth a try since tinnitus can be...
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    Improved transurethral medication for ED.

    ok, thanks I'll check it out. Hopefully they have a telemedicine option since i don't have a regular doctor.
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    Is my ED physical, psychological or hormonal?

    A general comment; erection quality is always a combination of things across the spectrum you listed, as well as others such as pheromone-like signaling from your partner. My approach and recommendation is to always be looking to maximize all of them as best you can. It's way too complicated to...
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    Took 4 days off my EOD injections and feel great. Need advice

    As Funk implies, there are simply too many variables and too little understanding of them to know what will happen, especially at the individual level, without experimentation. We have had posters here who seemed to do with injections at fairly long intervals so you may be one of those people.
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    Tinnitus

    Do you have a home montitor and have you done multiple readings at a time to see the fluctuation? What have you tried to bring it down?
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    Switched from TRT to Enclomiphene...surprising results

    Early in my TRT journey I used to come off for 6-8 weeks per year, and 6 weeks was usually not enough to recover my pre-TRT levels, so waiting some more and upping your dose (if it does not produce negative symptoms) seems reasonable. Also consider what else might affect your levels such as...

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