Regardless of whether the underlying research comes from industry, government or academia, the USP standard is federal law, which manufacturers and healthcare professionals presumably do not want to violate.Seems a point without any value.
Doesn't the USP manual derive it's recommendations from the testing the manufacture had done? It's basically just a cut and paste.
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I had a bottle open for a year or so I forgot about I was tired and placed it someplace weird lol and still used it and still works lol I just alcohol everything and go on lol
One approach is to divide the 10 mL vial into five vials of 2 mL each. That is, transfer 2 mL into each of four other sterile vials. If contamination is avoided in this step then each vial is almost like an unopened vial. In this example you're only using each vial for 50 days or less. I haven't tried the following to see if it's practical, but in transferring the contents of the original vial to other vials you might reduce the risk of contamination by using a separate 0.22 micron filter needle to equalize pressure as you draw the fluid. In this way you would avoid directly injecting room air into any vial.I've thought and posted about this before. I was eventually given a 10mL of 200mg/mL and I'm only using 8mg daily, so it's going to last months.
That's too much for me honestly. Would just using it for 60 days with sterile procedures be fine though?One approach is to divide the 10 mL vial into five vials of 2 mL each. That is, transfer 2 mL into each of four other sterile vials. If contamination is avoided in this step then each vial is almost like an unopened vial. In this example you're only using each vial for 50 days or less. I haven't tried the following to see if it's practical, but in transferring the contents of the original vial to other vials you might reduce the risk of contamination by using a separate 0.22 micron filter needle to equalize pressure as you draw the fluid. In this way you would avoid directly injecting room air into any vial.
Very likely, and it's something I would do without worrying too much. In the past I have used a single vial for many months, but now I would fret a little more about so many punctures of one stopper. Because I'm currently creating a TP/TE blend it's not much extra work to put the blend in a separate vial and limit the size to a month or so of use.That's too much for me honestly. Would just using it for 60 days with sterile procedures be fine though?